%0 Journal Article
%A Seth, Ajit
%A Giri, Rajendra P.
%A Hayen, Nicholas
%A hitaishi, prashant
%A Murphy, Bridget M.
%A Ghosh, Sajal K.
%T Cholesterol modulated assembly of graphene oxide nano-flakes at a phospholipid interface
%J Colloids and surfaces / B
%V 255
%@ 0927-7765
%C Amsterdam [u.a.]
%I Elsevier Science
%M PUBDB-2025-02347
%P 114934 
%D 2025
%X Cholesterol, a key structural component of mammalian cell membranes, is crucial in stabilizing the membraneand regulating its biophysical properties. Herein, the self-assembly of graphene oxide (GO) around differentlycharged lipid monolayers modulated by cholesterol has been investigated using surface pressure-area isothermsand synchrotron-based X-ray reflectivity. In pristine lipid monolayers, electrostatic interactions control the selfassemblyof GO nano-flakes around the lipid molecules. However, upon the addition of cholesterol, theadsorption and penetration kinetics of GO nano-flakes into the lipid monolayers are drastically amplified, irrespectiveof the ionic nature of lipids. The experimental observations are discussed in terms of interactionsoccurring among GO nano-flakes, phospholipids, and cholesterol molecules.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ pmid:40644792
%R 10.1016/j.colsurfb.2025.114934
%U https://bib-pubdb1.desy.de/record/633151