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@INPROCEEDINGS{Li:632812,
author = {Li, Chufeng and Ivanov, Nikolay and Prasciolu, Mauro and
Fleckenstein, Holger and Domaracky, Martin and Dresselhaus,
J. Lukas and Yefanov, Oleksandr and Zhang, Wenhui and
Zakharova, Margarita and Meents, Alke and Delmas, Tjark and
De Gennaro Aquino, Ivan and Oberthuer, Dominik and Sprenger,
Janina and Pateras, Anastasios and Henkel, Alessandra and
Mashhour, Aida Rahmani and Hakanpää, Johanna and Bajt,
Saša and Chapman, Henry N.},
title = {{C}onvergent beam {X}-ray crystallography and 3{D}
diffraction imaging using multilayer {L}aue lenses},
issn = {2053-2733},
reportid = {PUBDB-2025-02236},
year = {2023},
abstract = {crystallography and 3D diffraction microscopy. Our recent
MLLs achieve a numerical aperture (NA) of ~ 0.02 at a photon
energy of 17.5 keV (or 0.71 Å wavelength), meaning that
beam converges onto the focus over an angular range of 40
mrad or 1.3º. When the crystal is placed downstream of the
focus, there is a correlation between position in the beam
and the angle of incidence of a ray. The crystal selects
Bragg reflections from the supplied range of angles, at
particular locations of the crystal (slices, in the case of
a single crystal). In this configuration, the diffraction
data provides a mix of crystallography and (tomographic)
microscopy. We are particularly interested in developing
convergent-beam diffraction as a way to obtain
fully-integrated Bragg reflections in single exposures (to
reduce the number of patterns required in serial
crystallography at free-electron laser sources) and to
obtain structure factors of high accuracy by observing and
accounting for spatial variations in crystals, such as their
shape, strain, or defect structure. Additionally, using the
mapping between position and incidence angle, 3-D
microscopic images of the diffraction efficiency of the
crystal was obtained from the same data set. The simple
experimental setup and data collection strategy offers
advantages such as ample operational space and easy
adjustment of the spatial resolution by changing the
geometry. The convergent beam diffraction (CBD) scheme, with
further development in progress is potentially applicable to
multi-scale structural or dynamics studies for both material
and life sciences.},
month = {Aug},
date = {2023-08-22},
organization = {Twenty-Sixth Congress and General
Assembly of the International Union of
Crystallography, Melbourne (Australia),
22 Aug 2023 - 29 Aug 2023},
cin = {FS-CFEL-1 / FS-ML},
ddc = {530},
cid = {I:(DE-H253)FS-CFEL-1-20120731 / I:(DE-H253)FS-ML-20120731},
pnm = {633 - Life Sciences – Building Blocks of Life: Structure
and Function (POF4-633) / AIM, DFG project
G:(GEPRIS)390715994 - EXC 2056: CUI: Advanced Imaging of
Matter (390715994) / FS-Proposal: I-20231166 (I-20231166)},
pid = {G:(DE-HGF)POF4-633 / G:(GEPRIS)390715994 /
G:(DE-H253)I-20231166},
experiment = {EXP:(DE-H253)P-P11-20150101},
typ = {PUB:(DE-HGF)1},
doi = {10.1107/S2053273323092495},
url = {https://bib-pubdb1.desy.de/record/632812},
}