000628959 001__ 628959
000628959 005__ 20250723105925.0
000628959 0247_ $$2doi$$a10.1038/s41598-025-89431-0
000628959 0247_ $$2datacite_doi$$a10.3204/PUBDB-2025-01762
000628959 0247_ $$2pmid$$a40050327
000628959 0247_ $$2WOS$$aWOS:001439325200009
000628959 0247_ $$2openalex$$aopenalex:W4408175067
000628959 037__ $$aPUBDB-2025-01762
000628959 041__ $$aEnglish
000628959 082__ $$a600
000628959 1001_ $$0P:(DE-H253)PIP1032192$$aSchaeper, Jannis J.$$b0
000628959 245__ $$a3D virtual histology of rodent and primate cochleae with multi-scale phase-contrast X-ray tomography
000628959 260__ $$a[London]$$bSpringer Nature$$c2025
000628959 3367_ $$2DRIVER$$aarticle
000628959 3367_ $$2DataCite$$aOutput Types/Journal article
000628959 3367_ $$0PUB:(DE-HGF)16$$2PUB:(DE-HGF)$$aJournal Article$$bjournal$$mjournal$$s1748854127_1060025
000628959 3367_ $$2BibTeX$$aARTICLE
000628959 3367_ $$2ORCID$$aJOURNAL_ARTICLE
000628959 3367_ $$00$$2EndNote$$aJournal Article
000628959 520__ $$aMulti-scale X-ray phase contrast tomography (XPCT) enables three-dimensional (3D), non-destructive imaging of intact small animal cochlea and apical cochlear turns. Here we report on post-mortem imaging of excised non-human primate and rodent cochleae at different $μ$-CT and nano-CT synchrotron instruments. We explore different sample embeddings, stainings and imaging regimes. Under optimized conditions of sample preparation, instrumentation, imaging protocol, and phase retrieval, high image quality and detail level can be achieved in 3D reconstructions. The showcased instrumentation and imaging protocols along with the reconstucted volumes can serve as benchmarks and reference for multi-scale microanatomy and 3D histology. The provided benchmarks and imaging protocols of this work cover a wide range of scales and are intended as augmented imaging tools for auditory research. 
000628959 536__ $$0G:(DE-HGF)POF4-6G3$$a6G3 - PETRA III (DESY) (POF4-6G3)$$cPOF4-6G3$$fPOF IV$$x0
000628959 536__ $$0G:(DE-H253)I-20210562$$aFS-Proposal: I-20210562 (I-20210562)$$cI-20210562$$x1
000628959 536__ $$0G:(GEPRIS)390729940$$aDFG project G:(GEPRIS)390729940 - EXC 2067: Multiscale Bioimaging: Von molekularen Maschinen zu Netzwerken erregbarer Zellen (390729940)$$c390729940$$x2
000628959 536__ $$0G:(DE-Ds200)BMBF-05K22MG1$$a05K22MG1 - Methodische Entwicklung eines neuen Phasenkontrast-Tomographie Verfahrens mit holographischer Bildrekonstruktion (Holo-Tomographie). (BMBF-05K22MG1)$$cBMBF-05K22MG1$$f05K22MG1$$x3
000628959 536__ $$0G:(GEPRIS)317475864$$aDFG project G:(GEPRIS)317475864 - SFB 1286: Quantitative Synaptologie (317475864)$$c317475864$$x4
000628959 588__ $$aDataset connected to CrossRef, Journals: bib-pubdb1.desy.de
000628959 693__ $$0EXP:(DE-H253)P-P10-20150101$$1EXP:(DE-H253)PETRAIII-20150101$$6EXP:(DE-H253)P-P10-20150101$$aPETRA III$$fPETRA Beamline P10$$x0
000628959 7001_ $$0P:(DE-H253)PIP1090622$$aKampshoff, Christoph A.$$b1
000628959 7001_ $$0P:(DE-HGF)0$$aWolf, Bettina J.$$b2
000628959 7001_ $$0P:(DE-HGF)0$$aRoos, Lennart$$b3
000628959 7001_ $$0P:(DE-HGF)0$$aMichanski, Susann$$b4
000628959 7001_ $$0P:(DE-HGF)0$$aRuhwedel, Torben$$b5
000628959 7001_ $$0P:(DE-H253)PIP1082629$$aEckermann, Marina$$b6
000628959 7001_ $$0P:(DE-HGF)0$$aMeyer, Alexander$$b7
000628959 7001_ $$0P:(DE-HGF)0$$aJeschke, Marcus$$b8
000628959 7001_ $$0P:(DE-HGF)0$$aWichmann, Carolin$$b9
000628959 7001_ $$0P:(DE-H253)PIP1017922$$aMoser, Tobias$$b10
000628959 7001_ $$0P:(DE-H253)PIP1007848$$aSalditt, Tim$$b11$$eCorresponding author
000628959 773__ $$0PERI:(DE-600)2615211-3$$a10.1038/s41598-025-89431-0$$gVol. 15, no. 1, p. 7933$$n1$$p7933$$tScientific reports$$v15$$x2045-2322$$y2025
000628959 8564_ $$uhttps://bib-pubdb1.desy.de/record/628959/files/s41598-025-89431-0.pdf$$yOpenAccess
000628959 8564_ $$uhttps://bib-pubdb1.desy.de/record/628959/files/s41598-025-89431-0.pdf?subformat=pdfa$$xpdfa$$yOpenAccess
000628959 909CO $$ooai:bib-pubdb1.desy.de:628959$$pdnbdelivery$$pdriver$$pVDB$$popen_access$$popenaire
000628959 9101_ $$0I:(DE-HGF)0$$6P:(DE-H253)PIP1032192$$aExternal Institute$$b0$$kExtern
000628959 9101_ $$0I:(DE-HGF)0$$6P:(DE-H253)PIP1090622$$aExternal Institute$$b1$$kExtern
000628959 9101_ $$0I:(DE-HGF)0$$6P:(DE-H253)PIP1082629$$aExternal Institute$$b6$$kExtern
000628959 9101_ $$0I:(DE-HGF)0$$6P:(DE-H253)PIP1017922$$aExternal Institute$$b10$$kExtern
000628959 9101_ $$0I:(DE-HGF)0$$6P:(DE-H253)PIP1007848$$aExternal Institute$$b11$$kExtern
000628959 9131_ $$0G:(DE-HGF)POF4-6G3$$1G:(DE-HGF)POF4-6G0$$2G:(DE-HGF)POF4-600$$3G:(DE-HGF)POF4$$4G:(DE-HGF)POF$$aDE-HGF$$bForschungsbereich Materie$$lGroßgeräte: Materie$$vPETRA III (DESY)$$x0
000628959 9141_ $$y2025
000628959 915__ $$0StatID:(DE-HGF)0200$$2StatID$$aDBCoverage$$bSCOPUS$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)0160$$2StatID$$aDBCoverage$$bEssential Science Indicators$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)1050$$2StatID$$aDBCoverage$$bBIOSIS Previews$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)1190$$2StatID$$aDBCoverage$$bBiological Abstracts$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)0600$$2StatID$$aDBCoverage$$bEbsco Academic Search$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)1040$$2StatID$$aDBCoverage$$bZoological Record$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)0100$$2StatID$$aJCR$$bSCI REP-UK : 2022$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)0501$$2StatID$$aDBCoverage$$bDOAJ Seal$$d2024-07-29T15:28:26Z
000628959 915__ $$0StatID:(DE-HGF)0500$$2StatID$$aDBCoverage$$bDOAJ$$d2024-07-29T15:28:26Z
000628959 915__ $$0StatID:(DE-HGF)0113$$2StatID$$aWoS$$bScience Citation Index Expanded$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)0700$$2StatID$$aFees$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)0150$$2StatID$$aDBCoverage$$bWeb of Science Core Collection$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)9900$$2StatID$$aIF < 5$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)0510$$2StatID$$aOpenAccess
000628959 915__ $$0StatID:(DE-HGF)0030$$2StatID$$aPeer Review$$bASC$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)0561$$2StatID$$aArticle Processing Charges$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)1150$$2StatID$$aDBCoverage$$bCurrent Contents - Physical, Chemical and Earth Sciences$$d2024-12-18
000628959 915__ $$0StatID:(DE-HGF)0300$$2StatID$$aDBCoverage$$bMedline$$d2024-12-18
000628959 915__ $$0LIC:(DE-HGF)CCBY4$$2HGFVOC$$aCreative Commons Attribution CC BY 4.0
000628959 915__ $$0StatID:(DE-HGF)0199$$2StatID$$aDBCoverage$$bClarivate Analytics Master Journal List$$d2024-12-18
000628959 9201_ $$0I:(DE-H253)HAS-User-20120731$$kDOOR ; HAS-User$$lDOOR-User$$x0
000628959 980__ $$ajournal
000628959 980__ $$aVDB
000628959 980__ $$aUNRESTRICTED
000628959 980__ $$aI:(DE-H253)HAS-User-20120731
000628959 9801_ $$aFullTexts