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@ARTICLE{Leroux:619085,
author = {Leroux, Juliette and Chesnel, Jean-Yves and Ortiz-Mahecha,
Carlos and Nair, Aarathi and Oostenrijk, Bart Hendrik and
Pille, Laura and Trinter, Florian and Schwob, Lucas and
Bari, Sadia},
title = {{S}tructures of {G}as-{P}hase {H}ydrated {P}hosphotyrosine
{R}evealed by {S}oft {X}-ray {A}ction {S}pectroscopy},
journal = {Chemistry - a European journal},
volume = {31},
number = {10},
issn = {0947-6539},
address = {Weinheim},
publisher = {Wiley-VCH},
reportid = {PUBDB-2024-07372},
pages = {e202403665},
year = {2025},
abstract = {SectionsPDFToolsShareGraphical AbstractGas-phase near-edge
X-ray absorption mass spectrometry (NEXAMS) reveals the
effects of a single water molecule on protonated
phosphotyrosine at the carbon and oxygen K-edges. The water
molecule bonds with the phosphate group, altering the
spectral features. Comparisons with density functional
theory calculations identify three potential hydrated
structures.Description unavailableAbstractGas-phase
near-edge X-ray absorption mass spectrometry (NEXAMS) was
employed at the carbon and oxygen K-edges to probe the
influence of a single water molecule on the protonated
phosphotyrosine molecule. The results of the
photodissociation experiments revealed that the water
molecule forms two bonds, with the phosphate group and
another chemical group. By comparing the NEXAMS spectra at
the carbon and oxygen K-edges with density functional theory
calculations, we attributed the electronic transitions
responsible for the observed resonances, especially the
transitions due to the presence of the water molecule. We
showed that the water molecule leads to a specific spectral
feature in the partial ion yield of hydrated fragments at
536.4 eV. Moreover, comparing the NEXAMS spectra with the
calculated structures allowed us to identify three possible
structures for singly hydrated phosphotyrosine that agree
with the observed fragmentation and resonances.},
cin = {FS-BIG},
ddc = {660},
cid = {I:(DE-H253)FS-BIG-20220318},
pnm = {633 - Life Sciences – Building Blocks of Life: Structure
and Function (POF4-633) / FS-Proposal: I-20230427
(I-20230427) / DFG project G:(GEPRIS)509471550 - Dynamik
photoionisations-induzierter Prozesse in laser-präparierten
Molekülen in der Gasphase und der wässrigen Phase
(509471550) / AIM, DFG project G:(GEPRIS)390715994 - EXC
2056: CUI: Advanced Imaging of Matter (390715994) /
HIDSS-0002 - DASHH: Data Science in Hamburg - Helmholtz
Graduate School for the Structure of Matter
$(2019_IVF-HIDSS-0002)$},
pid = {G:(DE-HGF)POF4-633 / G:(DE-H253)I-20230427 /
G:(GEPRIS)509471550 / G:(GEPRIS)390715994 /
$G:(DE-HGF)2019_IVF-HIDSS-0002$},
experiment = {EXP:(DE-H253)P-P04-20150101},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:39757128},
UT = {WOS:001401184000001},
doi = {10.1002/chem.202403665},
url = {https://bib-pubdb1.desy.de/record/619085},
}