TY  - JOUR
AU  - Luo, Cheng
AU  - Vasudevan Namboodiri, Mahesh
AU  - Schulz, Michael
AU  - Riedel, Robert
AU  - Prandolini, Mark
AU  - Laarmann, Tim
TI  - Spectral fingerprinting of aqueous glucose with ultra-broadband vibrational sum-frequency generation spectroscopy at bio-relevant low concentration
JO  - Optics express
VL  - 33
IS  - 3
SN  - 1094-4087
CY  - Washington, DC
PB  - Optica
M1  - PUBDB-2024-06289
SP  - 6080 - 6091
PY  - 2025
AB  - Vibrational modes of glucose spanning from 900 to 1400 cm<sup>−1</sup> in the molecular fingerprint region have been traced by means of vibrational sum-frequency generation spectroscopy in aqueous solution as a function of glucose concentration. The high sensitivity is enabled by a 200 kHz few-cycle mid-infrared optical parametric chirped-pulse amplifier (OPCPA). The OPCPA generates broadband pulses (from 7 to 11 µm) centered at 9 µm with 114 fs pulse duration, at a high average power of 245 mW and high pulse energy of 1.2 µJ. The achieved performance of the spectrometer is benchmarked by probing the carbon-oxygen bond stretching mode at 1035 cm using a biologically relevant low sample concentration of 10 mM.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:001444162000001
DO  - DOI:10.1364/OE.544862
UR  - https://bib-pubdb1.desy.de/record/615828
ER  -