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@ARTICLE{Tomank:612577,
author = {Tomaník, Lukáš and Pugini, Michele and Mudryk, Karen and
Thuermer, Stephan and Stemer, Dominik and Credidio, Bruno
and Trinter, Florian and Winter, Bernd and Slavicek, Petr},
title = {{L}iquid-jet photoemission spectroscopy as a structural
tool: site-specific acid–base chemistry of vitamin {C}},
journal = {Physical chemistry, chemical physics},
volume = {26},
number = {29},
issn = {1463-9076},
address = {Cambridge},
publisher = {RSC Publ.},
reportid = {PUBDB-2024-05395},
pages = {19673-19684},
year = {2024},
note = {Open Access},
abstract = {Liquid-jet photoemission spectroscopy (LJ-PES) directly
probes the electronic structure of solutes and solvents. It
also emerges as a novel tool to explore chemical structure
in aqueous solutions, yet the scope of the approach has to
be examined. Here, we present a pH-dependent liquid-jet
photoelectron spectroscopic investigation of ascorbic acid
(vitamin C). We combine core-level photoelectron
spectroscopy and ab initio calculations, allowing us to
site-specifically explore the acid–base chemistry of the
biomolecule. For the first time, we demonstrate the
capability of the method to simultaneously assign two
deprotonation sites within the molecule. We show that a
large change in chemical shift appears even for atoms
distant several bonds from the chemically modified group.
Furthermore, we present a highly efficient and accurate
computational protocol based on a single structure using the
maximum-overlap method for modeling core-level photoelectron
spectra in aqueous environments. This work poses a broader
question: to what extent can LJ-PES complement established
structural techniques such as nuclear magnetic resonance?
Answering this question is highly relevant in view of the
large number of incorrect molecular structures published.},
cin = {DOOR ; HAS-User / FS-PETRA-S},
ddc = {540},
cid = {I:(DE-H253)HAS-User-20120731 /
I:(DE-H253)FS-PETRA-S-20210408},
pnm = {6G3 - PETRA III (DESY) (POF4-6G3) / AQUACHIRAL - Chiral
aqueous-phase chemistry (883759) / DFG project 509471550 -
Dynamik photoionisations-induzierter Prozesse in
laser-präparierten Molekülen in der Gasphase und der
wässrigen Phase (509471550)},
pid = {G:(DE-HGF)POF4-6G3 / G:(EU-Grant)883759 /
G:(GEPRIS)509471550},
experiment = {EXP:(DE-H253)P-P04-20150101},
typ = {PUB:(DE-HGF)16},
pubmed = {38963770},
UT = {WOS:001261898700001},
doi = {10.1039/D4CP01521E},
url = {https://bib-pubdb1.desy.de/record/612577},
}