%0 Journal Article
%A Johny, Melby
%A Schouder, Constant A.
%A Al-Refaie, Ahmed
%A He, Lanhai
%A Wiese, Joss
%A Stapelfeldt, Henrik
%A Trippel, Sebastian
%A Küpper, Jochen
%T Water is a radiation protection agent for ionised pyrrole
%J Physical chemistry, chemical physics
%V 26
%N 17
%@ 1463-9076
%C Cambridge
%I RSC Publ.
%M PUBDB-2024-01291
%M arXiv:2010.00453
%P 13118-13130
%D 2024
%X Radiation-induced damage of biological matter is an ubiquitous problem in nature. The influence   of the hydration environment is widely discussed, but its exact role remains elusive. Utilising   well defined solvated-molecule aggregates, we experimentally observed a hydrogen-bonded water   molecule acting as a radiation protection agent for ionised pyrrole, a prototypical aromatic   biomolecule. Pure samples of pyrrole and pyrrole(H<sub>2</sub>O) were outer-valence ionised and the subsequent   damage and relaxation processes were studied. Bare pyrrole ions fragmented through the breaking   of C−C or N−C covalent bonds. However, for pyrrole(H<sub>2</sub>O)<sup>+</sup>, we observed a strong protection of the   pyrrole ring through the dissociative release of neutral water or by transferring an electron or   proton across the hydrogen bond. Overall, a single water molecule strongly reduces the   fragmentation probability and thus the persistent radiation damage of singly-ionised pyrrole.
%F PUB:(DE-HGF)16
%9 Journal Article
%$ 38629233
%U <Go to ISI:>//WOS:001204249800001
%R 10.1039/D3CP03471B
%U https://bib-pubdb1.desy.de/record/605016