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@ARTICLE{Fink:604167,
author = {Fink, Lea and Steiner, Ariel and Szekely, Or and Szekely,
Pablo and Raviv, Uri},
title = {{S}tructure and {I}nteractions between {C}harged {L}ipid
{M}embranes in the {P}resence of {M}ultivalent {I}ons},
journal = {Langmuir},
volume = {35},
number = {30},
issn = {0743-7463},
address = {Washington, DC},
publisher = {ACS Publ.},
reportid = {PUBDB-2024-01026},
pages = {9694 - 9703},
year = {2019},
abstract = {When aqueous salt solutions contain multivalent ions (like
Ca2+ or Mg2+), strong correlation effects may lead to
ion-bridging, net attraction, and tight-coupling between
like-charged interfaces. To examine the effects of surface
charge density, temperature, salt type, and salt
concentration on the structures of tightly coupled charged
interfaces, we have used mixed lipid membranes, containing
either saturated or unsaturated tails in the presence of
multivalent ions. We discovered that tightly coupled
membrane lamellar phases, dominated by attractive
interactions, coexisted with weakly coupled lamellar phases,
dominated by repulsive interactions. To control the membrane
charge density, we mixed lipids with negatively charged
headgroups, DLPS and DOPS, with their zwitterionic analogue
having the same tails, DLPC and DOPC, respectively. Using
solution X-ray scattering we measured the lamellar repeat
distance, D, at different ion concentrations, temperatures,
and membrane charge densities. The multivalent ions tightly
coupled the mixed lipid bilayers whose charged lipid molar
fraction was between 0.1 and 1. The repeat distance of the
tightly coupled phase was about 4 nm for the DLPS/DLPC
mixtures and about 5 nm for the DOPS/DOPC mixtures. In this
phase, the repeat distance slightly increased with
increasing temperature and decreased with increasing charge
density. When the molar fraction of charged lipid was 0.1 or
0.25, a less tightly coupled phase coexisted with the
tightly coupled phase. The weakly coupled lamellar phase had
significantly larger D values, although they were
consistently shorter than the D values in monovalent salt
solutions with similar screening lengths.},
cin = {DOOR ; HAS-User},
ddc = {540},
cid = {I:(DE-H253)HAS-User-20120731},
pnm = {899 - ohne Topic (POF4-899)},
pid = {G:(DE-HGF)POF4-899},
experiment = {EXP:(DE-H253)D-D1.2-20150101},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:31283884},
UT = {WOS:000479019700006},
doi = {10.1021/acs.langmuir.9b00778},
url = {https://bib-pubdb1.desy.de/record/604167},
}