TY  - JOUR
AU  - Gharib, Mustafa
AU  - Kornowski, Andreas
AU  - Noei, Heshmat
AU  - Parak, Wolfgang
AU  - Chakraborty, Indranath
TI  - Protein-Protected Porous Bimetallic AgPt Nanoparticles with pH-Switchable Peroxidase/Catalase-Mimicking Activity
JO  - ACS materials letters
VL  - 1
IS  - 3
SN  - 2639-4979
CY  - Washington, DC
PB  - ACS Publications
M1  - PUBDB-2024-00930
SP  - 310 - 319
PY  - 2019
AB  - Bovine serum albumin (BSA)-protected AgPt bimetallic nanoparticles have been synthesized through a galvanic replacement reaction, using a silver nanoprism as a template. Synthesis was performed without the use of synthetic chemical surfactants, using proteins as a surface coating. Structural and compositional characterizations were performed using several spectroscopic and microscopic techniques. The protein-protected AgPt nanoparticles show effective pH-switchable enzyme mimicking (“nanozyme”) activity similar to catalase and peroxidase. The platinum content in the AgPt nanoparticles is playing an important role in determining the enzymatic catalysis rate of the nanoparticles. Because of their porous structure, molecular payloads such as calcein also can be incorporated into the AgPt nanoparticles, which can be released on demand by chemical triggers, such as hydrogen peroxide.
LB  - PUB:(DE-HGF)16
UR  - <Go to ISI:>//WOS:000519670000004
DO  - DOI:10.1021/acsmaterialslett.9b00164
UR  - https://bib-pubdb1.desy.de/record/603745
ER  -