TY  - JOUR
AU  - Yu, Dingquan
AU  - Chojnowski, Grzegorz
AU  - Rosenthal, Maria
AU  - Kosinski, Jan
TI  - AlphaPulldown—a python package for protein–protein interaction screens using AlphaFold-Multimer
JO  - Bioinformatics
VL  - 39
IS  - 1
SN  - 0266-7061
CY  - Oxford
PB  - Oxford Univ. Press
M1  - PUBDB-2024-00574
SP  - btac749
PY  - 2023
N1  - This work was supported by the German Research Foundation (DFG) [KO 5979/2-1].
AB  - The artificial intelligence-based structure prediction program AlphaFold-Multimer enabled structural modelling of protein complexes with unprecedented accuracy. Increasingly, AlphaFold-Multimer is also used to discover new protein–protein interactions (PPIs). Here, we present AlphaPulldown, a Python package that streamlines PPI screens and high-throughput modelling of higher-order oligomers using AlphaFold-Multimer. It provides a convenient command-line interface, a variety of confidence scores and a graphical analysis tool. 
LB  - PUB:(DE-HGF)16
C6  - pmid:36413069
UR  - <Go to ISI:>//WOS:000892528500001
DO  - DOI:10.1093/bioinformatics/btac749
UR  - https://bib-pubdb1.desy.de/record/602299
ER  -