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000602299 1001_ $$0P:(DE-H253)PIP1094728$$aYu, Dingquan$$b0
000602299 245__ $$aAlphaPulldown—a python package for protein–protein interaction screens using AlphaFold-Multimer
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000602299 500__ $$aThis work was supported by the German Research Foundation (DFG) [KO 5979/2-1].
000602299 520__ $$aThe artificial intelligence-based structure prediction program AlphaFold-Multimer enabled structural modelling of protein complexes with unprecedented accuracy. Increasingly, AlphaFold-Multimer is also used to discover new protein–protein interactions (PPIs). Here, we present AlphaPulldown, a Python package that streamlines PPI screens and high-throughput modelling of higher-order oligomers using AlphaFold-Multimer. It provides a convenient command-line interface, a variety of confidence scores and a graphical analysis tool.
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000602299 7001_ $$0P:(DE-HGF)0$$aChojnowski, Grzegorz$$b1
000602299 7001_ $$0P:(DE-HGF)0$$aRosenthal, Maria$$b2
000602299 7001_ $$0P:(DE-H253)PIP1081584$$aKosinski, Jan$$b3$$eCorresponding author
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