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@ARTICLE{Jiang:602025,
author = {Jiang, Xuehe and Mietner, J. Benedikt and Raveendran,
Dhanya and Ovchinnikov, Kirill V. and Sochor, Benedikt and
Mueller, Susanne and Boehm-Sturm, Philipp and Lerouge,
Frédéric and Chaput, Frédéric and Gurikov, Pavel and
Roth, Stephan V. and Navarro, Julien R.G.},
title = {{M}ultifunctional {C}ellulose {N}anofibrils–{G}d{F}$_3$
{N}anoparticles {H}ybrid {G}el and {I}ts {P}otential {U}ses
for {D}rug {D}elivery and {M}agnetic {R}esonance {I}maging},
journal = {ACS applied nano materials},
volume = {6},
number = {22},
issn = {2574-0970},
address = {Washington, DC},
publisher = {ACS Publications},
reportid = {PUBDB-2024-00473},
pages = {21182 - 21193},
year = {2023},
note = {Waiting for fulltext},
abstract = {A multifunctional hybrid gel based on cellulose nanofibrils
(CNFs) was developed by grafting on its surface stearyl
acrylate (PSA) and gadolinium(III) fluoride nanoparticles
(GdF$_3$ NPs) via Cu$^{0}$-mediated surface-initiated
radical polymerization (SET-LRP) while encapsulating
antimicrobial peptides in it. GdF$_3$ NPs were first
surface-modified with 11-phosphonoundecyl acrylate (PDA) to
participate in the SET-LRP and cross-linked the grafted
polymer-modified CNF. Several characterizations of the
hybrid material (GdF$_3$–PSA-CNF) were carried out, such
as Fourier transform infrared (FTIR) spectroscopy,
thermogravimetric analysis (TGA), rheology, and microscopic
analyses. The grafted PSA and cross-linked GdF$_3$ NPs
created sophisticated networks in the CNF-based gel,
presenting outstanding rheological properties and promising
three-dimensional (3D) printability of this hybrid material
(GdF$_3$–PSA-CNF). The nanostructures of GdF$_3$ NPs and
their incorporated CNF species were characterized via
small-angle X-ray scattering (SAXS). In addition, due to the
unique intrinsic property of the GdF$_3$ nanoparticles,
properties for magnetic resonance imaging (MRI) of
GdF$_3$–PSA-CNF were investigated, showing the potential
application as a contrast agent. Finally, the encapsulation
of the antimicrobial peptides added another function to the
hybrid material, evaluated by an antimicrobial test against
methicillin-resistant Staphylococcus aureus (MRSA) in
vitro.},
cin = {DOOR ; HAS-User / FS-PET-D / FS-SMA},
ddc = {540},
cid = {I:(DE-H253)HAS-User-20120731 / I:(DE-H253)FS-PET-D-20190712
/ I:(DE-H253)FS-SMA-20220811},
pnm = {632 - Materials – Quantum, Complex and Functional
Materials (POF4-632) / 6G3 - PETRA III (DESY) (POF4-6G3) /
DFG project 390688087 - EXC 2049: Comprehensive approaches
to neurological and psychiatric disorders "NeuroCure"
(390688087)},
pid = {G:(DE-HGF)POF4-632 / G:(DE-HGF)POF4-6G3 /
G:(GEPRIS)390688087},
experiment = {EXP:(DE-H253)P-P03-20150101},
typ = {PUB:(DE-HGF)16},
UT = {WOS:001109825100001},
doi = {10.1021/acsanm.3c04272},
url = {https://bib-pubdb1.desy.de/record/602025},
}