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@ARTICLE{He:599503,
author = {He, Lanhai and Tomaník, Lukáš and Malerz, Sebastian and
Trinter, Florian and Trippel, Sebastian and Belina, Michal
and Slavicek, Petr and Winter, Bernd and Küpper, Jochen},
title = {{S}pecific versus {N}onspecific {S}olvent {I}nteractions of
a {B}iomolecule in {W}ater},
journal = {The journal of physical chemistry letters},
volume = {14},
number = {46},
issn = {1948-7185},
address = {Washington, DC},
publisher = {ACS},
reportid = {PUBDB-2023-07453},
pages = {10499 - 10508},
year = {2023},
abstract = {Solvent interactions, particularly hydration, are vital in
chemical and biochemical systems. Model systems reveal
microscopic details of such interactions. We uncover a
specific hydrogen-bonding motif of the biomolecular building
block indole (C8H7N), tryptophan’s chromophore, in water:
a strong localized N–H···OH2 hydrogen bond, alongside
unstructured solvent interactions. This insight is revealed
from a combined experimental and theoretical analysis of the
electronic structure of indole in aqueous solution. We
recorded the complete X-ray photoemission and Auger spectrum
of aqueous-phase indole, quantitatively explaining all peaks
through ab initio modeling. The efficient and accurate
technique for modeling valence and core photoemission
spectra involves the maximum-overlap method and the
nonequilibrium polarizable-continuum model. A two-hole
electron-population analysis quantitatively describes the
Auger spectra. Core–electron binding energies for nitrogen
and carbon highlight the specific interaction with a
hydrogen-bonded water molecule at the N–H group and
otherwisenonspecific solvent interactions.},
cin = {FS-CFEL-CMI / FS-PETRA-S / DOOR ; HAS-User},
ddc = {530},
cid = {I:(DE-H253)FS-CFEL-CMI-20220405 /
I:(DE-H253)FS-PETRA-S-20210408 /
I:(DE-H253)HAS-User-20120731},
pnm = {631 - Matter – Dynamics, Mechanisms and Control
(POF4-631) / 6G3 - PETRA III (DESY) (POF4-6G3) / DFG project
390715994 - EXC 2056: CUI: Advanced Imaging of Matter
(390715994) / COMOTION - Controlling the Motion of Complex
Molecules and Particles (614507) / AQUACHIRAL - Chiral
aqueous-phase chemistry (883759) / DFG project 194651731 -
EXC 1074: Hamburger Zentrum für ultraschnelle Beobachtung
(CUI): Struktur, Dynamik und Kontrolle von Materie auf
atomarer Skala (194651731)},
pid = {G:(DE-HGF)POF4-631 / G:(DE-HGF)POF4-6G3 /
G:(GEPRIS)390715994 / G:(EU-Grant)614507 /
G:(EU-Grant)883759 / G:(GEPRIS)194651731},
experiment = {EXP:(DE-H253)P-P04-20150101},
typ = {PUB:(DE-HGF)16},
pubmed = {37970807},
UT = {WOS:001141297100001},
doi = {10.1021/acs.jpclett.3c01763},
url = {https://bib-pubdb1.desy.de/record/599503},
}