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@ARTICLE{Ginn:578456,
author = {Ginn, Helen},
title = {{T}orsion angles to map and visualize the conformational
space of a protein},
journal = {Protein science},
volume = {32},
number = {4},
issn = {0961-8368},
address = {Bethesda, Md.},
publisher = {Protein Society},
reportid = {PUBDB-2023-00952},
pages = {e4608},
year = {2023},
note = {License CC-BY},
abstract = {Present understanding of protein structure dynamics trails
behind that of static structures. A torsion angle based
approach, called representation of protein entities (RoPE),
derives an interpretable conformational space which
correlates with data collection temperature, resolution and
reaction coordinate. For more complex systems, atomic
coordinates fail to separate functional conformational
states, which are still preserved by torsion angle-derived
space. This indicates that torsion angles are often a more
sensitive and biologically relevant descriptor for protein
conformational dynamics than atomic coordinates.},
cin = {FS-CFEL-1 / FS-CFEL-1-DNMX},
ddc = {610},
cid = {I:(DE-H253)FS-CFEL-1-20120731 /
I:(DE-H253)FS-CFEL-1-DNMX-20231108},
pnm = {633 - Life Sciences – Building Blocks of Life: Structure
and Function (POF4-633)},
pid = {G:(DE-HGF)POF4-633},
experiment = {EXP:(DE-H253)CFEL-Exp-20150101},
typ = {PUB:(DE-HGF)16},
pubmed = {36840926},
UT = {WOS:000949309400001},
doi = {10.1002/pro.4608},
url = {https://bib-pubdb1.desy.de/record/578456},
}