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001     491479
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024 7 _ |a 10.1038/s41592-022-01760-4
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100 1 _ |a Lane, Thomas
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245 _ _ |a Protein structure prediction has reached the single-structure frontier
260 _ _ |a London [u.a.]
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520 _ _ |a Dramatic advances in protein structure prediction have sparked debate as to whether the problem of predicting structure from sequence is solved or not. Here, I argue that AlphaFold2 and its peers are currently limited by the fact that they predict only a single structure, instead of a structural distribution, and that this realization is crucial for the next generation of structure prediction algorithms.
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773 _ _ |a 10.1038/s41592-022-01760-4
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856 4 _ |y Published on 2023-01-13. Available in OpenAccess from 2023-07-13.
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