TY  - JOUR
AU  - Lane, Thomas
TI  - Protein structure prediction has reached the single-structure frontier
JO  - Nature methods
VL  - 20
IS  - 2
SN  - 1548-7091
CY  - London [u.a.]
PB  - Nature Publishing Group
M1  - PUBDB-2023-00183
SP  - 170 - 173
PY  - 2023
AB  - Dramatic advances in protein structure prediction have sparked debate as to whether the problem of predicting structure from sequence is solved or not. Here, I argue that AlphaFold2 and its peers are currently limited by the fact that they predict only a single structure, instead of a structural distribution, and that this realization is crucial for the next generation of structure prediction algorithms.
LB  - PUB:(DE-HGF)16
C6  - 36639584
UR  - <Go to ISI:>//WOS:000913553400001
DO  - DOI:10.1038/s41592-022-01760-4
UR  - https://bib-pubdb1.desy.de/record/491479
ER  -