TY - JOUR AU - Villanueva-Perez, P. AU - Fleckenstein, Holger AU - Prasciolu, Mauro AU - Murray, K. T. AU - Domaracky, Martin AU - Gregoric, Klara AU - Mariani, Valerio AU - Gelisio, Luca AU - Kuhn, Manuela AU - Hannappel, Juergen AU - Yefanov, Oleksandr AU - Ivanov, Nikolay AU - Sarrou, Iosifina AU - Pennicard, David AU - Becker, Julian AU - von Zimmermann, Martin AU - Gutowski, Olof AU - Dippel, Ann-Christin AU - Chapman, H. N. AU - Bajt, S. TI - Scanning Compton X-ray microscopy JO - Optics letters VL - 46 IS - 8 SN - 0146-9592 CY - Washington, DC PB - Soc. M1 - PUBDB-2021-01606 SP - 1920 - 1923 PY - 2021 N1 - Pablo Villanueve-Perez - now at: Synchrotron Radiation Research and NanoLund, Lund University, Box 118, 221 00, Lund, Sweden AB - X-ray microscopy offers the opportunity to image biological and radiosensitive materials without special sample preparations, bridging optical and electron microscopy capabilities. However, the performance of such microscopes, when imaging radiosensitive samples, is not limited by their intrinsic resolution, but by the radiation damage induced on such samples. Here, we demonstrate a novel, to the best of our knowledge, radio-efficient microscope, scanning Compton X-ray microscopy (SCXM), which uses coherently and incoherently (Compton) scattered photons to minimize the deposited energy per unit of mass for a given imaging signal. We implemented SCXM, using lenses capable of efficiently focusing 60 keV X-ray photons into the sub-micrometer scale, and probe its radio-efficient capabilities. SCXM, when implemented in high-energy diffraction-limited storage rings, e.g., European Synchrotron Radiation Facility Extremely Brilliant Source and PETRA IV, will open the opportunity to explore the nanoscale of unstained, unsectioned, and undamaged radiosensitive materials. LB - PUB:(DE-HGF)16 C6 - pmid:33857104 UR - <Go to ISI:>//WOS:000640370200033 DO - DOI:10.1364/OL.421232 UR - https://bib-pubdb1.desy.de/record/456666 ER -