TY  - JOUR
AU  - Kuczera, Stefan
AU  - Rüter, Axel
AU  - Roger, Kevin
AU  - Olsson, Ulf
TI  - Two Dimensional Oblique Molecular Packing within a Model Peptide Ribbon Aggregate
JO  - ChemPhysChem
VL  - 21
IS  - 14
SN  - 1439-7641
CY  - Weinheim
PB  - Wiley-VCH Verl.
M1  - PUBDB-2020-04448
SP  - 1519-1523
PY  - 2020
AB  - A<sub>10</sub>K (A=alanine, K=lysine) model peptides self‐assemble into ribbon‐like β‐sheet aggregates. Here, we report an X‐ray diffraction investigation on a flow‐aligned dispersion of these self‐assembly structures. The two‐dimensional wide‐angle X‐ray scattering pattern suggests that peptide pack in a two‐dimensional oblique lattice, essentially identical to the crystalline packing of polyalanine, A<sub>n</sub> (for n>4). One side of the oblique unit cell, corresponding to the anti‐parallel β‐sheet, is oriented along the ribbon's axis. Together with recently published small angle X‐ray scattering data of the same system, this work thus yields a detailed description of the self‐assembled ribbon aggregates, down to the molecular length scale. Notably, our results highlight the importance of the crystalline peptide packing within its self‐assembly aggregates, which is often neglected. 
LB  - PUB:(DE-HGF)16
C6  - pmid:32573909
UR  - <Go to ISI:>//WOS:000541875900001
DO  - DOI:10.1002/cphc.201901126
UR  - https://bib-pubdb1.desy.de/record/451989
ER  -