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@ARTICLE{Woiska:421174,
author = {Woińska, Magdalena and Grabowsky, Simon and Dominiak,
Paulina M. and Woźniak, Krzysztof and Jayatilaka, Dylan},
title = {{H}ydrogen atoms can be located accurately and precisely by
x-ray crystallography},
journal = {Science advances},
volume = {2},
number = {5},
issn = {2375-2548},
address = {Washington, DC [u.a.]},
publisher = {AAAS},
reportid = {PUBDB-2019-01883},
pages = {e1600192 -},
year = {2016},
abstract = {recise and accurate structural information on hydrogen
atoms is crucial to the study of energies of interactions
important for crystal engineering, materials science,
medicine, and pharmacy, and to the estimation of physical
and chemical properties in solids. However, hydrogen atoms
only scatter x-radiation weakly, so x-rays have not been
used routinely to locate them accurately. Textbooks and
teaching classes still emphasize that hydrogen atoms cannot
be located with x-rays close to heavy elements; instead,
neutron diffraction is needed. We show that, contrary to
widespread expectation, hydrogen atoms can be located very
accurately using x-ray diffraction, yielding bond lengths
involving hydrogen atoms (A–H) that are in agreement with
results from neutron diffraction mostly within a single
standard deviation. The precision of the determination is
also comparable between x-ray and neutron diffraction
results. This has been achieved at resolutions as low as 0.8
Å using Hirshfeld atom refinement (HAR). We have applied
HAR to 81 crystal structures of organic molecules and
compared the A–H bond lengths with those from neutron
measurements for A–H bonds sorted into bonds of the same
class. We further show in a selection of inorganic compounds
that hydrogen atoms can be located in bridging positions and
close to heavy transition metals accurately and precisely.
We anticipate that, in the future, conventional x-radiation
sources at in-house diffractometers can be used routinely
for locating hydrogen atoms in small molecules accurately
instead of large-scale facilities such as spallation sources
or nuclear reactors.},
cin = {DOOR},
ddc = {500},
cid = {I:(DE-H253)HAS-User-20120731},
pnm = {899 - ohne Topic (POF3-899)},
pid = {G:(DE-HGF)POF3-899},
experiment = {EXP:(DE-H253)D-D3-20150101},
typ = {PUB:(DE-HGF)16},
pubmed = {pmid:27386545},
UT = {WOS:000380073000031},
doi = {10.1126/sciadv.1600192},
url = {https://bib-pubdb1.desy.de/record/421174},
}