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@INPROCEEDINGS{Chia:415778,
      author       = {Chia, Shih-Hsuan and Chung, Hsiang-Yu and Liu, Wei and
                      Kärtner, Franz and Chang, Guoqing},
      title        = {{D}eep {T}issue {M}ultiphoton {M}icroscopy {B}ased on
                      {A}dvanced {F}emtosecond {F}iber {S}ources},
      address      = {[Piscataway, NJ]},
      publisher    = {IEEE},
      reportid     = {PUBDB-2018-04681},
      isbn         = {978-1-5386-6605-0},
      pages        = {4},
      year         = {2018},
      note         = {IEEE},
      comment      = {2018 20th International Conference on Transparent Optical
                      Networks (ICTON) : [Proceedings] - IEEE, 2018. - ISBN
                      978-1-5386-6605-0 - doi:10.1109/ICTON.2018.8474004},
      booktitle     = {2018 20th International Conference on
                       Transparent Optical Networks (ICTON) :
                       [Proceedings] - IEEE, 2018. - ISBN
                       978-1-5386-6605-0 -
                       doi:10.1109/ICTON.2018.8474004},
      abstract     = {The use of multiphoton microscopy has proven its potential
                      on deep tissue virtual biopsy for early diagnosis and
                      neuronal processes imaging. However, the capability of
                      multiphoton microscopy strongly depends on the availability
                      of easily operated femtosecond laser sources. By precise
                      management of fiber-optic nonlinearity, we have demonstrated
                      the way to generate nearly transform-limited femtosecond
                      sources with the tunable wavelength range of 0.9 μm - 1.2
                      μm, covering both the GFP two-photon-excitation band and
                      transparency window of common bio-tissues. The demonstrated
                      approach is fully energy scalable to sub-100 nJ level of
                      pulse energy with the spectral tunable range down to 1.31
                      μm, which paves the way to capture deep-tissue imaging
                      contrast from third harmonic generation and
                      three-photon-excited GFP fluorescence. We applied such an
                      energetic source to a proof-of-principle study of ex vivo
                      human skin based on harmonics (i.e., second-harmonic
                      generation and third-harmonic generation) imaging. This new
                      type of fiber-format energetic ultrafast source will be
                      performed as a robust solution for multiphoton microscopy
                      applications, as well as studying the damage assessments
                      from thermal heating and multiphoton absorption during the
                      imaging process.},
      month         = {Jul},
      date          = {2018-07-01},
      organization  = {20th International Conference on
                       Transparent Optical Networks, Bucharest
                       (Romania), 1 Jul 2018 - 5 Jul 2018},
      cin          = {CFEL-ULOCM / FS-CFEL-2 / UNI/CUI},
      cid          = {I:(DE-H253)CFEL-ULOCM-20160928 /
                      I:(DE-H253)FS-CFEL-2-20120731 /
                      $I:(DE-H253)UNI_CUI-20121230$},
      pnm          = {6211 - Extreme States of Matter: From Cold Ions to Hot
                      Plasmas (POF3-621) / CUI - Hamburger Zentrum für
                      ultraschnelle Beobachtung (194651731)},
      pid          = {G:(DE-HGF)POF3-6211 / G:(GEPRIS)194651731},
      experiment   = {EXP:(DE-H253)CFEL-Exp-20150101},
      typ          = {PUB:(DE-HGF)8 / PUB:(DE-HGF)7},
      doi          = {10.1109/ICTON.2018.8474004},
      url          = {https://bib-pubdb1.desy.de/record/415778},
}