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@ARTICLE{Chung:408614,
author = {Chung, Hsiang-Yu and Cao, Qian and Greinert, Rudiger and
Kartner, Franz X. and Chang, Guoqing and Liu, Wei},
title = {{T}unable, {U}ltrafast {F}iber-{L}aser {B}etween 1.15 and
1.35 $\mu$m for {H}armonic {G}eneration {M}icroscopy in
{H}uman {S}kin},
journal = {IEEE journal of selected topics in quantum electronics},
volume = {25},
number = {1},
issn = {1077-260X},
address = {New York, NY},
publisher = {IEEE},
reportid = {PUBDB-2018-02981},
pages = {6800708},
year = {2018},
abstract = {We demonstrate a fiber-optic ultrafast tunable source for
harmonic generation microscopy (HGM) in human skin. The
source is based on a 31-MHz Er-fiber laser followed
byself-phase modulation enabled spectral selection (SESS).
The resulting pulses are tunable between 1.15 and 1.35 μm
with up to >10-nJ pulse energy and ∼100-fs pulse duration.
We employ this source to drive a scanning microscope for HGM
imaging of ex vivo human skin. A systematic investigation on
imaging depth versus excitation wavelength reveals that
excitation wavelengths in the 1.15–1.25 μm range exhibit
low optical attenuation within the tissue and allows larger
imaging depth for HGM in human skin.HGM driven by
fiber-based SESS sources constitutes an enabling tool for
noninvasive virtual skin biopsy in clinical applications.},
cin = {CFEL-ULOCM / FS-CFEL-2},
ddc = {530},
cid = {I:(DE-H253)CFEL-ULOCM-20160928 /
I:(DE-H253)FS-CFEL-2-20120731},
pnm = {6211 - Extreme States of Matter: From Cold Ions to Hot
Plasmas (POF3-621)},
pid = {G:(DE-HGF)POF3-6211},
experiment = {EXP:(DE-MLZ)NOSPEC-20140101},
typ = {PUB:(DE-HGF)16},
UT = {WOS:000443143200001},
doi = {10.1109/JSTQE.2018.2864193},
url = {https://bib-pubdb1.desy.de/record/408614},
}