% IMPORTANT: The following is UTF-8 encoded.  This means that in the presence
% of non-ASCII characters, it will not work with BibTeX 0.99 or older.
% Instead, you should use an up-to-date BibTeX implementation like “bibtex8” or
% “biber”.

@ARTICLE{Song:390512,
      author       = {Song, Miryoung and Sukovich, David J. and Ciccarelli,
                      Luciano and Mayr, Julia and Fernandez-Rodriguez, Jesus and
                      Mirsky, Ethan A. and Tucker, Alex C. and Gordon, D. Benjamin
                      and Marlovits, Thomas C. and Voigt, Christopher A.},
      title        = {{C}ontrol of type {III} protein secretion using a minimal
                      genetic system},
      journal      = {Nature Communications},
      volume       = {8},
      issn         = {2041-1723},
      address      = {London},
      publisher    = {Macmillan},
      reportid     = {PUBDB-2017-09604},
      pages        = {14737},
      year         = {2017},
      abstract     = {Gram-negative bacteria secrete proteins using a type III
                      secretion system (T3SS), which functions as a needle-like
                      molecular machine. The many proteins involved in T3SS
                      construction are tightly regulated due to its role in
                      pathogenesis and motility. Here, starting with the 35 kb
                      Salmonella pathogenicity island 1 (SPI-1), we eliminated
                      internal regulation and simplified the genetics by removing
                      or recoding genes, scrambling gene order and replacing all
                      non-coding DNA with synthetic genetic parts. This process
                      results in a 16 kb cluster that shares no sequence
                      identity, regulation or organizational principles with
                      SPI-1. Building this simplified system led to the discovery
                      of essential roles for an internal start site (SpaO) and
                      small RNA (InvR). Further, it can be controlled using
                      synthetic regulatory circuits, including under SPI-1
                      repressing conditions. This work reveals an incredible
                      post-transcriptional robustness in T3SS assembly and aids
                      its control as a tool in biotechnology.},
      cin          = {CSSB-UKE / CSSB-UKE-TM},
      ddc          = {500},
      cid          = {I:(DE-H253)CSSB-UKE-20141216 /
                      I:(DE-H253)CSSB-UKE-TM-20210520},
      pnm          = {6215 - Soft Matter, Health and Life Sciences (POF3-621)},
      pid          = {G:(DE-HGF)POF3-6215},
      experiment   = {EXP:(DE-MLZ)NOSPEC-20140101},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000400846400001},
      pubmed       = {pmid:28485369},
      doi          = {10.1038/ncomms14737},
      url          = {https://bib-pubdb1.desy.de/record/390512},
}