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100 1 _ |a Zarrine-Afsar, Arash
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245 _ _ |a Crystallography on a chip
260 _ _ |a Oxford
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520 _ _ |a A new chip-based crystal-mounting approach for rapid room-temperature data collection from numerous crystals is described. This work was motivated by the recent development of X-ray free-electron lasers. These novel sources deliver very intense femtosecond X-ray pulses that promise to yield high-resolution diffraction data of nanocrystals before their destruction by radiation damage. Thus, the concept of `diffraction before destruction' requires rapid replenishment of the sample for each exposure. The chip promotes the self-assembly of an array of protein crystals on a surface. Rough features on the surface cause the crystals to adopt random orientations, allowing efficient sampling of reciprocal space.
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700 1 _ |a Barends, Thomas R. M.
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700 1 _ |a Müller, Christina
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700 1 _ |a Fuchs, Martin R.
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700 1 _ |a Lomb, Lukas
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700 1 _ |a Schlichting, Ilme
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700 1 _ |a Miller, R. J. Dwayne
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773 _ _ |a 10.1107/S0907444911055296
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|t Acta crystallographica / D
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