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000300245 1001_ $$0P:(DE-HGF)0$$aZarrine-Afsar, Arash$$b0$$eCorresponding author
000300245 245__ $$aCrystallography on a chip
000300245 260__ $$aOxford$$bWiley-Blackwell$$c2012
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000300245 520__ $$aA new chip-based crystal-mounting approach for rapid room-temperature data collection from numerous crystals is described. This work was motivated by the recent development of X-ray free-electron lasers. These novel sources deliver very intense femtosecond X-ray pulses that promise to yield high-resolution diffraction data of nanocrystals before their destruction by radiation damage. Thus, the concept of `diffraction before destruction' requires rapid replenishment of the sample for each exposure. The chip promotes the self-assembly of an array of protein crystals on a surface. Rough features on the surface cause the crystals to adopt random orientations, allowing efficient sampling of reciprocal space.
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000300245 7001_ $$0P:(DE-HGF)0$$aBarends, Thomas R. M.$$b1
000300245 7001_ $$0P:(DE-HGF)0$$aMüller, Christina$$b2
000300245 7001_ $$0P:(DE-HGF)0$$aFuchs, Martin R.$$b3
000300245 7001_ $$0P:(DE-H253)PIP1008257$$aLomb, Lukas$$b4
000300245 7001_ $$0P:(DE-H253)PIP1008260$$aSchlichting, Ilme$$b5
000300245 7001_ $$0P:(DE-H253)PIP1012317$$aMiller, R. J. Dwayne$$b6
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