guest ::
| Home > Publications database > A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide > print |
| Home > Publications database > A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide > print |
| 001 | 293440 | ||
| 005 | 20210709143651.0 | ||
| 024 | 7 | _ | |a 10.1038/nsmb.2935 |2 doi |
| 024 | 7 | _ | |a 1072-8368 |2 ISSN |
| 024 | 7 | _ | |a 1545-9985 |2 ISSN |
| 024 | 7 | _ | |a 1545-9993 |2 ISSN |
| 024 | 7 | _ | |a WOS:000347664700010 |2 WOS |
| 024 | 7 | _ | |a pmid:25504321 |2 pmid |
| 024 | 7 | _ | |a altmetric:2984407 |2 altmetric |
| 037 | _ | _ | |a PUBDB-2016-00529 |
| 082 | _ | _ | |a 570 |
| 100 | 1 | _ | |a Hagelueken, Gregor |b 0 |
| 245 | _ | _ | |a A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide |
| 260 | _ | _ | |a London [u.a.] |c 2014 |b Nature Publishing Group |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1470228481_29732 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 500 | _ | _ | |a (c) Macmillan Publishers Limited. Post referee full text in progress. |
| 520 | _ | _ | |a Long-chain bacterial polysaccharides have important roles in pathogenicity. In Escherichia coli O9a, a model for ABC transporter–dependent polysaccharide assembly, a large extracellular carbohydrate with a narrow size distribution is polymerized from monosaccharides by a complex of two proteins, WbdA (polymerase) and WbdD (terminating protein). Combining crystallography and small-angle X-ray scattering, we found that the C-terminal domain of WbdD contains an extended coiled-coil that physically separates WbdA from the catalytic domain of WbdD. The effects of insertions and deletions in the coiled-coil region were analyzed in vivo, revealing that polymer size is controlled by varying the length of the coiled-coil domain. Thus, the coiled-coil domain of WbdD functions as a molecular ruler that, along with WbdA:WbdD stoichiometry, controls the chain length of a model bacterial polysaccharide. |
| 536 | _ | _ | |a 899 - ohne Topic (POF3-899) |0 G:(DE-HGF)POF3-899 |c POF3-899 |f POF III |x 0 |
| 588 | _ | _ | |a Dataset connected to CrossRef |
| 693 | _ | _ | |a DORIS III |e Facility (machine) DORIS III |1 EXP:(DE-H253)DORISIII-20150101 |0 EXP:(DE-H253)DORISIII(machine)-20150101 |5 EXP:(DE-H253)DORISIII(machine)-20150101 |x 0 |
| 700 | 1 | _ | |a Clarke, Bradley R |0 0000-0003-2233-1268 |b 1 |
| 700 | 1 | _ | |a Huang, Hexian |b 2 |
| 700 | 1 | _ | |a Tuukkanen, Anne |b 3 |
| 700 | 1 | _ | |a Danciu, Iulia |b 4 |
| 700 | 1 | _ | |a Svergun, Dmitri |0 P:(DE-H253)PIP1001422 |b 5 |
| 700 | 1 | _ | |a Hussain, Rohanah |0 P:(DE-HGF)0 |b 6 |
| 700 | 1 | _ | |a Liu, Huanting |b 7 |
| 700 | 1 | _ | |a Whitfield, Chris |0 P:(DE-HGF)0 |b 8 |e Corresponding author |
| 700 | 1 | _ | |a Naismith, James H |0 P:(DE-HGF)0 |b 9 |e Corresponding author |
| 773 | _ | _ | |a 10.1038/nsmb.2935 |g Vol. 22, no. 1, p. 50 - 56 |0 PERI:(DE-600)2131437-8 |n 1 |p 50 - 56 |t Nature structural & molecular biology |v 22 |y 2014 |x 1545-9985 |
| 909 | C | O | |p VDB |o oai:bib-pubdb1.desy.de:293440 |
| 910 | 1 | _ | |a Europäisches Laboratorium für Molekularbiologie |0 I:(DE-588b)235011-7 |k EMBL |b 5 |6 P:(DE-H253)PIP1001422 |
| 913 | 1 | _ | |a DE-HGF |b Programmungebundene Forschung |l ohne Programm |1 G:(DE-HGF)POF3-890 |0 G:(DE-HGF)POF3-899 |2 G:(DE-HGF)POF3-800 |v ohne Topic |x 0 |4 G:(DE-HGF)POF |3 G:(DE-HGF)POF3 |
| 915 | _ | _ | |a Nationallizenz |0 StatID:(DE-HGF)0420 |2 StatID |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0200 |2 StatID |b SCOPUS |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0300 |2 StatID |b Medline |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0310 |2 StatID |b NCBI Molecular Biology Database |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0199 |2 StatID |b Thomson Reuters Master Journal List |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0110 |2 StatID |b Science Citation Index |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)0150 |2 StatID |b Web of Science Core Collection |
| 915 | _ | _ | |a WoS |0 StatID:(DE-HGF)0111 |2 StatID |b Science Citation Index Expanded |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1030 |2 StatID |b Current Contents - Life Sciences |
| 915 | _ | _ | |a DBCoverage |0 StatID:(DE-HGF)1050 |2 StatID |b BIOSIS Previews |
| 915 | _ | _ | |a JCR |0 StatID:(DE-HGF)0100 |2 StatID |b NAT STRUCT MOL BIOL : 2014 |
| 915 | _ | _ | |a IF >= 10 |0 StatID:(DE-HGF)9910 |2 StatID |b NAT STRUCT MOL BIOL : 2014 |
| 920 | 1 | _ | |0 I:(DE-H253)EMBL-20120731 |k EMBL |l EMBL |x 0 |
| 920 | 1 | _ | |0 I:(DE-H253)EMBL-User-20120814 |k EMBL-User |l EMBL-User |x 1 |
| 980 | _ | _ | |a journal |
| 980 | _ | _ | |a VDB |
| 980 | _ | _ | |a I:(DE-H253)EMBL-20120731 |
| 980 | _ | _ | |a I:(DE-H253)EMBL-User-20120814 |
| 980 | _ | _ | |a UNRESTRICTED |
| Library | Collection | CLSMajor | CLSMinor | Language | Author |
|---|