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| 001 | 220265 | ||
| 005 | 20250717105523.0 | ||
| 024 | 7 | _ | |a 10.1063/1.4919398 |2 doi |
| 024 | 7 | _ | |a WOS:000360649200005 |2 WOS |
| 024 | 7 | _ | |a pmid:26798803 |2 pmid |
| 024 | 7 | _ | |a altmetric:3953412 |2 altmetric |
| 024 | 7 | _ | |a openalex:W1991313455 |2 openalex |
| 037 | _ | _ | |a PUBDB-2015-02182 |
| 082 | _ | _ | |a 530 |
| 100 | 1 | _ | |a Galli, Lorenzo |0 P:(DE-H253)PIP1013871 |b 0 |
| 245 | _ | _ | |a Electronic damage in S atoms in a native protein crystal induced by an intense X-ray free-electron laser pulse |
| 260 | _ | _ | |a Melville, NY |c 2015 |b AIP Publishing LLC |
| 336 | 7 | _ | |a article |2 DRIVER |
| 336 | 7 | _ | |a Output Types/Journal article |2 DataCite |
| 336 | 7 | _ | |a Journal Article |b journal |m journal |0 PUB:(DE-HGF)16 |s 1480921499_25134 |2 PUB:(DE-HGF) |
| 336 | 7 | _ | |a ARTICLE |2 BibTeX |
| 336 | 7 | _ | |a JOURNAL_ARTICLE |2 ORCID |
| 336 | 7 | _ | |a Journal Article |0 0 |2 EndNote |
| 500 | _ | _ | |a OA |
| 520 | _ | _ | |a Current hard X-ray free-electron laser (XFEL) sources can deliver doses to biological macromolecules well exceeding 1 GGy, in timescales of a few tens of femtoseconds. During the pulse, photoionization can reach the point of saturation in which certain atomic species in the sample lose most of their electrons. This electronic radiation damage causes the atomic scattering factors to change, affecting, in particular, the heavy atoms, due to their higher photoabsorption cross sections. Here, it is shown that experimental serial femtosecond crystallography data collected with an extremely bright XFEL source exhibit a reduction of the effective scattering power of the sulfur atoms in a native protein. Quantitative methods are developed to retrieve information on the effective ionization of the damaged atomic species from experimental data, and the implications of utilizing new phasing methods which can take advantage of this localized radiation damage are discussed. |
| 536 | _ | _ | |a 6211 - Extreme States of Matter: From Cold Ions to Hot Plasmas (POF3-621) |0 G:(DE-HGF)POF3-6211 |c POF3-621 |f POF III |x 0 |
| 536 | _ | _ | |a 05K13GU7 - Test eines "Serial Femtosecond Crystallography (SFX)"-Messtandes am Europäischen Elektronenlaser XFEL (BMBF-05K13GU7) |0 G:(DE-H253)BMBF-05K13GU7 |c BMBF-05K13GU7 |x 1 |
| 536 | _ | _ | |0 G:(DE-HGF)2015_IFV-VH-GS-500 |x 2 |c 2015_IFV-VH-GS-500 |a VH-GS-500 - PIER Helmholtz Graduate School (2015_IFV-VH-GS-500) |
| 588 | _ | _ | |a Dataset connected to CrossRef |
| 693 | _ | _ | |0 EXP:(DE-MLZ)NOSPEC-20140101 |5 EXP:(DE-MLZ)NOSPEC-20140101 |e No specific instrument |x 0 |
| 700 | 1 | _ | |a Son, S.-K. |0 P:(DE-H253)PIP1012452 |b 1 |
| 700 | 1 | _ | |a Klinge, M. |b 2 |
| 700 | 1 | _ | |a Bajt, S. |0 P:(DE-H253)PIP1006443 |b 3 |u desy |
| 700 | 1 | _ | |a Barty, A. |0 P:(DE-H253)PIP1008245 |b 4 |u desy |
| 700 | 1 | _ | |a Bean, Richard |0 P:(DE-H253)PIP1016993 |b 5 |
| 700 | 1 | _ | |a Betzel, C. |b 6 |
| 700 | 1 | _ | |a Beyerlein, Kenneth |0 P:(DE-H253)PIP1016189 |b 7 |u desy |
| 700 | 1 | _ | |a Caleman, C. |0 P:(DE-H253)PIP1011740 |b 8 |u desy |
| 700 | 1 | _ | |a Doak, R. B. |b 9 |
| 700 | 1 | _ | |a Duszenko, M. |b 10 |
| 700 | 1 | _ | |a Fleckenstein, H. |0 P:(DE-H253)PIP1011659 |b 11 |u desy |
| 700 | 1 | _ | |a Gati, C. |0 P:(DE-H253)PIP1017962 |b 12 |
| 700 | 1 | _ | |a Hunt, B. |b 13 |
| 700 | 1 | _ | |a Kirian, R. A. |b 14 |
| 700 | 1 | _ | |a Liang, M. |b 15 |
| 700 | 1 | _ | |a Nanao, M. H. |b 16 |
| 700 | 1 | _ | |a Nass, K. |b 17 |
| 700 | 1 | _ | |a Oberthür, D. |0 P:(DE-H253)PIP1012087 |b 18 |u desy |
| 700 | 1 | _ | |a Redecke, L. |b 19 |
| 700 | 1 | _ | |a Shoeman, R. |b 20 |
| 700 | 1 | _ | |a Stellato, F. |0 P:(DE-H253)PIP1011192 |b 21 |u desy |
| 700 | 1 | _ | |a Yoon, C. H. |0 P:(DE-H253)PIP1016300 |b 22 |u desy |
| 700 | 1 | _ | |a White, T. A. |0 P:(DE-H253)PIP1010779 |b 23 |u desy |
| 700 | 1 | _ | |a Yefanov, O. |0 P:(DE-H253)PIP1006155 |b 24 |u desy |
| 700 | 1 | _ | |a Spence, J. |b 25 |
| 700 | 1 | _ | |a Chapman, H. N. |0 P:(DE-H253)PIP1006324 |b 26 |e Corresponding author |
| 773 | _ | _ | |a 10.1063/1.4919398 |g Vol. 2, no. 4, p. 041703 - |0 PERI:(DE-600)2758684-4 |n 4 |p 041703 |t Structural dynamics |v 2 |y 2015 |x 2329-7778 |
| 856 | 4 | _ | |y OpenAccess |
| 856 | 4 | _ | |u https://bib-pubdb1.desy.de/record/220265/files/1.4919398.pdf |y OpenAccess |
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| 910 | 1 | _ | |a The European X-Ray Laser Project XFEL |0 I:(DE-588b)16047298-2 |k XFEL |b 0 |6 P:(DE-H253)PIP1013871 |
| 910 | 1 | _ | |a Deutsches Elektronen-Synchrotron |0 I:(DE-588b)2008985-5 |k DESY |b 1 |6 P:(DE-H253)PIP1012452 |
| 910 | 1 | _ | |a Centre for Free-Electron Laser Science |0 I:(DE-H253)_CFEL-20120731 |k CFEL |b 1 |6 P:(DE-H253)PIP1012452 |
| 910 | 1 | _ | |a Deutsches Elektronen-Synchrotron |0 I:(DE-588b)2008985-5 |k DESY |b 3 |6 P:(DE-H253)PIP1006443 |
| 910 | 1 | _ | |a Centre for Free-Electron Laser Science |0 I:(DE-H253)_CFEL-20120731 |k CFEL |b 3 |6 P:(DE-H253)PIP1006443 |
| 910 | 1 | _ | |a Deutsches Elektronen-Synchrotron |0 I:(DE-588b)2008985-5 |k DESY |b 4 |6 P:(DE-H253)PIP1008245 |
| 910 | 1 | _ | |a Centre for Free-Electron Laser Science |0 I:(DE-H253)_CFEL-20120731 |k CFEL |b 4 |6 P:(DE-H253)PIP1008245 |
| 910 | 1 | _ | |a European XFEL |0 I:(DE-588)1043621512 |k XFEL.EU |b 5 |6 P:(DE-H253)PIP1016993 |
| 910 | 1 | _ | |a Deutsches Elektronen-Synchrotron |0 I:(DE-588b)2008985-5 |k DESY |b 7 |6 P:(DE-H253)PIP1016189 |
| 910 | 1 | _ | |a Centre for Free-Electron Laser Science |0 I:(DE-H253)_CFEL-20120731 |k CFEL |b 7 |6 P:(DE-H253)PIP1016189 |
| 910 | 1 | _ | |a Deutsches Elektronen-Synchrotron |0 I:(DE-588b)2008985-5 |k DESY |b 8 |6 P:(DE-H253)PIP1011740 |
| 910 | 1 | _ | |a Centre for Free-Electron Laser Science |0 I:(DE-H253)_CFEL-20120731 |k CFEL |b 8 |6 P:(DE-H253)PIP1011740 |
| 910 | 1 | _ | |a Deutsches Elektronen-Synchrotron |0 I:(DE-588b)2008985-5 |k DESY |b 11 |6 P:(DE-H253)PIP1011659 |
| 910 | 1 | _ | |a Centre for Free-Electron Laser Science |0 I:(DE-H253)_CFEL-20120731 |k CFEL |b 11 |6 P:(DE-H253)PIP1011659 |
| 910 | 1 | _ | |a Centre for Free-Electron Laser Science |0 I:(DE-H253)_CFEL-20120731 |k CFEL |b 12 |6 P:(DE-H253)PIP1017962 |
| 910 | 1 | _ | |a Europäisches Laboratorium für Molekularbiologie |0 I:(DE-588b)235011-7 |k EMBL |b 12 |6 P:(DE-H253)PIP1017962 |
| 910 | 1 | _ | |a Deutsches Elektronen-Synchrotron |0 I:(DE-588b)2008985-5 |k DESY |b 18 |6 P:(DE-H253)PIP1012087 |
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| 910 | 1 | _ | |a Centre for Free-Electron Laser Science |0 I:(DE-H253)_CFEL-20120731 |k CFEL |b 22 |6 P:(DE-H253)PIP1016300 |
| 910 | 1 | _ | |a Deutsches Elektronen-Synchrotron |0 I:(DE-588b)2008985-5 |k DESY |b 23 |6 P:(DE-H253)PIP1010779 |
| 910 | 1 | _ | |a Centre for Free-Electron Laser Science |0 I:(DE-H253)_CFEL-20120731 |k CFEL |b 23 |6 P:(DE-H253)PIP1010779 |
| 910 | 1 | _ | |a Deutsches Elektronen-Synchrotron |0 I:(DE-588b)2008985-5 |k DESY |b 24 |6 P:(DE-H253)PIP1006155 |
| 910 | 1 | _ | |a Centre for Free-Electron Laser Science |0 I:(DE-H253)_CFEL-20120731 |k CFEL |b 24 |6 P:(DE-H253)PIP1006155 |
| 910 | 1 | _ | |a Europäisches Laboratorium für Molekularbiologie |0 I:(DE-588b)235011-7 |k EMBL |b 24 |6 P:(DE-H253)PIP1006155 |
| 910 | 1 | _ | |a Deutsches Elektronen-Synchrotron |0 I:(DE-588b)2008985-5 |k DESY |b 26 |6 P:(DE-H253)PIP1006324 |
| 910 | 1 | _ | |a Centre for Free-Electron Laser Science |0 I:(DE-H253)_CFEL-20120731 |k CFEL |b 26 |6 P:(DE-H253)PIP1006324 |
| 913 | 1 | _ | |a DE-HGF |b Forschungsbereich Materie |l Von Materie zu Materialien und Leben |1 G:(DE-HGF)POF3-620 |0 G:(DE-HGF)POF3-621 |2 G:(DE-HGF)POF3-600 |v In-house research on the structure, dynamics and function of matter |9 G:(DE-HGF)POF3-6211 |x 0 |4 G:(DE-HGF)POF |3 G:(DE-HGF)POF3 |
| 914 | 1 | _ | |y 2015 |
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