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100 1 _ |a Pospisilova, Aneta
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245 _ _ |a Glycogen-graft-poly(2-alkyl-2-oxazolines) - The new Versatile Biopolymer-Based Thermoresponsive Macromolecular Toolbox
260 _ _ |a London
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520 _ _ |a his study is focused on thermoresponsive glycogen-graft-poly(2-alkyl-2-oxazolines), a new group of nanostructured hybrid dendrimeric stimuli-responsive polymers connecting the body's own biodegradable polysaccharidic dendrimer glycogen with the widely tuneable thermoresponsive behavior of polypeptide-analogic poly(2-alkyl-2-oxazolines), which are known to be biocompatible. Glycogen-graft-poly(2-alkyl-2-oxazolines) were prepared by a simple one-pot two-step procedure involving cationic ring-opening polymerization of 2-alkyl-2-oxazolines followed by termination of the living cationic ends with sodium glycogenate. As confirmed by light and X-ray scattering, as well as cryo-transmission electron microscopy, the grafted dendrimer structure allows easy adjustment of the cloud point temperature, the concentration dependence and nanostructure of the self-assembled phase separated polymer by crosstalk during graft composition, the graft length and the grafting density, in a very wide range.
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700 1 _ |a Filippov, Sergey
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700 1 _ |a Bogomolova, Anna
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700 1 _ |a Turner, Stuart
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700 1 _ |a Sedlacek, Ondrej
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700 1 _ |a Matushkin, Nikolai
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700 1 _ |a Cernochova, Zulfia
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700 1 _ |a Stepanek, Petr
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700 1 _ |a Hruby, Martin
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773 _ _ |a 10.1039/c4ra10315g
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