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@ARTICLE{Eulenburg:166792,
      author       = {Eulenburg, Georg and Higman, Victoria A. and Diehl, Anne
                      and Wilmanns, Matthias and Holton, Simon J.},
      title        = {{S}tructural and biochemical characterization of {R}v2140c,
                      a phosphatidylethanolamine-binding protein from
                      {M}ycobacterium tuberculosis},
      journal      = {FEBS letters},
      volume       = {587},
      number       = {18},
      issn         = {0014-5793},
      address      = {Amsterdam [u.a.]},
      publisher    = {Elsevier},
      reportid     = {DESY-2014-01626},
      pages        = {2936 - 2942},
      year         = {2013},
      note         = {(c) Federation of European Biochemical Societies; Post
                      referee fulltext in progress; Embargo 12 months from
                      publication},
      abstract     = {Rv2140c is one of many conserved Mycobacterium tuberculosis
                      proteins for which no molecular function has been
                      identified. We have determined a high-resolution crystal
                      structure of the Rv2140c gene product, which reveals a
                      dimeric complex that shares strong structural homology with
                      the phosphatidylethanolamine-binding family of proteins.
                      Rv2140c forms low-millimolar interactions with a selection
                      of soluble phosphatidylethanolamine analogs, indicating that
                      it has a role in lipid metabolism. Furthermore, the small
                      molecule locostatin binds to the Rv2140c ligand-binding site
                      and also inhibits the growth of the model organism
                      Mycobacterium smegmatis.},
      cin          = {EMBL},
      ddc          = {570},
      cid          = {I:(DE-H253)EMBL-20120731},
      pnm          = {DORIS Beamline BW7 (POF2-54G13)},
      pid          = {G:(DE-H253)POF2-BW7-20130405},
      experiment   = {EXP:(DE-H253)D-BW7-20150101},
      typ          = {PUB:(DE-HGF)16},
      UT           = {WOS:000324033700007},
      pubmed       = {pmid:23907008},
      doi          = {10.1016/j.febslet.2013.07.038},
      url          = {https://bib-pubdb1.desy.de/record/166792},
}