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We present the result of a search for the charged-lepton-flavor violating decays τ$^{−}$→ e$^{∓}$ℓ$^{±}$ℓ$^{−}$, where ℓ is a muon or an electron, using a data sample with an integrated luminosity of 428 fb$^{−1}$ recorded by the Belle II experiment at the SuperKEKB e$^{+}$e$^{−}$ collider. The selection of e$^{+}$e$^{−}$→ τ$^{+}$τ$^{−}$ events containing a signal candidate is based on an inclusive-tagging reconstruction and on a boosted decision tree to suppress background.Upper limits on the branching fractions between 1.3 and 2.5 × 10$^{−8}$ are set at the 90% confidence level [...]

We present a determination of the Cabibbo-Kobayashi-Maskawa matrix element |Vcb| from the decay B→Dℓνℓ using a 365 fb-1 e+e-→ϒ(4S)→BB¯ data sample recorded by the Belle II experiment at the SuperKEKB collider. The semileptonic decay of one B meson is reconstructed in the modes B0→D-(→K+π-π-)ℓ+νℓ and B+→D¯0(→K+π-)ℓ+νℓ, where ℓ denotes either an electron or a muon. [...]

Bempedoic acid (BA) is a recently approved drug that lowers cholesterol and hepatic lipids, yet its mechanism of action remains incompletely understood. Here, we combine transcriptomic, biochemical, and structural approaches to show that BA directly binds to and activates peroxisome proliferator-activated receptor alpha (PPARα). [...]

We present a search for the rare flavor-changing neutral-current decay B0→K*0τ+τ- with data collected by the Belle II experiment at the SuperKEKB electron-positron collider. The analysis uses a 365 fb-1 data sample recorded at the center-of-mass energy of the ϒ(4S) resonance. [...]

We report a measurement of the branching fraction for the leptonic decay $B^+\toμ^+ν_μ$. This work presents the first $B^+\toμ^+ν_μ$ result using Belle~II data, an updated Belle measurement that supersedes the previous result, and their combination, which yields the most precise search to date. [...]

HintergrundDie konventionelle histopathologische Diagnostik stößt bei der Beurteilung komplexer, dreidimensionaler Gewebearchitekturen an inhärente methodische Grenzen. Insbesondere bei heterogen zusammengesetzten Geweben wie dem Pankreas oder bei komplexen Gewebspathologien erschwert die Beschränkung auf zweidimensionale Schnittbilder die ubiquitäre Erfassung morphologischer Merkmale.Ziel der Arbeit (Fragestellung)Ziel dieser Studie ist es, das Potenzial der synchrotronbasierten Phasenkontrastbildgebung (SRµCT) für die hochauflösende, dreidimensionale Visualisierung verschiedener Pankreasgewebe zu demonstrieren. [...]

The High Granularity Calorimeter (HGCAL) will replace the existing Calorimeter Endcaps of the CMS detector as part of the upgrade program for HL-LHC. Proposed for the High Luminosity era, HGCAL’s design addresses its challenges by taking advantage of the radiation tolerance of silicon sensors and advances in the fields of mechanical and electrical engineering. [...]