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A sample of 365 fb-1 of e+e-→ϒ(4S)→BB¯ data collected by the Belle II experiment is used to measure the partial branching fractions of charmless semileptonic B meson decays and determine the magnitude of the Cabibbo-Kobayashi-Maskawa (CKM) matrix element Vub. Events containing a signal electron or muon ℓ and a fully reconstructed hadronic B decay that constrains the signal kinematics are selected, while the rest of the event defines the hadronic system Xu associated with the signal. [...]

We present a measurement of the time-dependent CP asymmetry in ${B}^{0}\to {K}_{\text{S}}^{0}{\pi }^{+}{\pi }^{-}\gamma $ decays using a data set of 365 fb$^{−1}$ recorded by the Belle II experiment and the final data set of 711 fb$^{−1}$ recorded by the Belle experiment at the Υ(4S) resonance. The direct and mixing-induced time-dependent CP violation parameters C and S are determined along with two additional quantities, S$^{+}$ and S$^{−}$, defined in the two halves of the ${m}^{2}\left({K}_{\text{S}}^{0}{\pi }^{+}\right)-{m}^{2}\left({K}_{\text{S}}^{0}{\pi }^{-}\right)$ plane [...]

We present the result of a search for the charged-lepton-flavor violating decays τ$^{−}$→ e$^{∓}$ℓ$^{±}$ℓ$^{−}$, where ℓ is a muon or an electron, using a data sample with an integrated luminosity of 428 fb$^{−1}$ recorded by the Belle II experiment at the SuperKEKB e$^{+}$e$^{−}$ collider. The selection of e$^{+}$e$^{−}$→ τ$^{+}$τ$^{−}$ events containing a signal candidate is based on an inclusive-tagging reconstruction and on a boosted decision tree to suppress background.Upper limits on the branching fractions between 1.3 and 2.5 × 10$^{−8}$ are set at the 90% confidence level [...]

We present a determination of the Cabibbo-Kobayashi-Maskawa matrix element |Vcb| from the decay B→Dℓνℓ using a 365 fb-1 e+e-→ϒ(4S)→BB¯ data sample recorded by the Belle II experiment at the SuperKEKB collider. The semileptonic decay of one B meson is reconstructed in the modes B0→D-(→K+π-π-)ℓ+νℓ and B+→D¯0(→K+π-)ℓ+νℓ, where ℓ denotes either an electron or a muon. [...]

Bempedoic acid (BA) is a recently approved drug that lowers cholesterol and hepatic lipids, yet its mechanism of action remains incompletely understood. Here, we combine transcriptomic, biochemical, and structural approaches to show that BA directly binds to and activates peroxisome proliferator-activated receptor alpha (PPARα). [...]

We present a search for the rare flavor-changing neutral-current decay B0→K*0τ+τ- with data collected by the Belle II experiment at the SuperKEKB electron-positron collider. The analysis uses a 365 fb-1 data sample recorded at the center-of-mass energy of the ϒ(4S) resonance. [...]

Using a data sample of 427.9 fb$^{-1}$ collected by the Belle~II detector at or near the $Υ(4S)$ and $Υ(10753)$ resonances, the cross sections for $e^+e^-\to h^+h^-J/ψ$$(h=π/K/p)$ at center-of-mass energies ranging from 3.8 GeV or the production threshold to 5.5/6.0/7.0 GeV have been measured via initial-state radiation. The cross sections for the processes $e^+e^-\to π^+π^-J/ψ$ and $e^+e^-\to K^+K^-J/ψ$ are consistent with previously published results. [...]

We report a measurement of the branching fraction for the leptonic decay $B^+\toμ^+ν_μ$. This work presents the first $B^+\toμ^+ν_μ$ result using Belle~II data, an updated Belle measurement that supersedes the previous result, and their combination, which yields the most precise search to date. [...]

HintergrundDie konventionelle histopathologische Diagnostik stößt bei der Beurteilung komplexer, dreidimensionaler Gewebearchitekturen an inhärente methodische Grenzen. Insbesondere bei heterogen zusammengesetzten Geweben wie dem Pankreas oder bei komplexen Gewebspathologien erschwert die Beschränkung auf zweidimensionale Schnittbilder die ubiquitäre Erfassung morphologischer Merkmale.Ziel der Arbeit (Fragestellung)Ziel dieser Studie ist es, das Potenzial der synchrotronbasierten Phasenkontrastbildgebung (SRµCT) für die hochauflösende, dreidimensionale Visualisierung verschiedener Pankreasgewebe zu demonstrieren. [...]

Titin kinase (TK) is an enigmatic pseudokinase specific to the striated muscle of vertebrates. Embedded within the contractile sarcomere and flanked by extensible regulatory tails, TK is thought to act as a mechanoreceptor that senses mechanical signals arising from muscle function. [...]