Contribution to a conference proceedings/Contribution to a book

PUBDB-2023-08019

http://join2-wiki.gsi.de/foswiki/pub/Main/Artwork/join2_logo100x88.png Comparison of measurements and simulation results of dose for the FLASH radiation therapy beamline at PITZ

Amirkhanyan, Z. G. (Corresponding author)Extern*DESY* ; Aftab, N.DESY* ; Adhikari, G. D.DESY* ; Boonpornprasert, P.DESY* ; Georgiev, G.DESY* ; Grebinyk, A.DESY* ; Gross, M.DESY* ; Hoffmann, A.XFEL.EU*DESY* ; Krasilnikov, M.DESY* ; Kuhl, T.DESY* ; Li, X.DESY* ; Oppelt, A.DESY* ; Philipp, S.DESY* ; Riemer, F.DESY* ; Richard, C. J.DESY* ; Vashchenko, G.DESY* ; Stephan, F.DESY* ; Khachatryan, V.

2023
JACoW Publishing Geneva
ISBN: 978-3-95450-231-8

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Please use a persistent id in citations: doi:10.18429/JACoW-IPAC2023-THPM049  doi:10.3204/PUBDB-2023-08019

Abstract: The high-brightness electron beam at the Photo Injector Test facility at DESY in Zeuthen (PITZ) is now also used for FLASHlab@PITZ: an R&D platform for studying radiation biology and the FLASH effect in radiation therapy. The available parameter space of the electron beam with a momentum of 22 MeV/c allows bunch charges from 10 pC up to 5nC, bunch duration of 0.1–60ps, and bunch train lengths up to 1 ms. The number of bunches in the single train can currently be varied between 1 and 1000 bunches, with an upgrade to 4500 foreseen in 2023. Radiation biology studies require accurate dose prediction, therefore Monte Carlo simulations based on the FLUKA code were performed. According to estimations, dose delivery of 0.002Gy (low charge case 0.1pC) and 10Gy (high charge case 5nC) is possible, if the beam is confined to a circular area with a radius of 5 mm with a lead collimator. For the Monte Carlo simulations, the experimental setup was accurately modeled, including the exit window, lead collimator, etc. Dose measurements were used to compare simulations with experiments. Dose profiles were experimentally measured with Gafchromic films and then compared with Monte Carlo simulations. The first experiments at FLASHlab@PITZ in 2023 have demonstrated flexible dose options for studying the FLASH effect and radiation biology studies

Keyword(s): Accelerator Physics ; mc8-applications-of-accelerators-technology-transfer-and-industrial-relations-and-outreach - MC8: Applications of Accelerators, Technology Transfer and Industrial Relations and Outreach ; mc8-u11-radiation-effects-testing-facilities-and-strategies - MC8.U11: Radiation Effects – Testing Facilities and Strategies

Note: Literaturangaben;

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Contributing Institute(s):

1. Technologie (Z_PITZ)
2. Z_DET (Z_DET)

Research Program(s):

1. 621 - Accelerator Research and Development (POF4-621) (POF4-621)

Experiment(s):

1. Photo Injector Test Facility

Appears in the scientific report 2023

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