DFG project G:(GEPRIS)141518795
The interplay between Toll-like receptors, interferons and hepatitis B virus (A01)
| Coordinator | Professor Dr. Youhua Xie ; Professor Dr. Zheng-Hong Yuan |
| Grant period | - 2017 |
| Funding body | Deutsche Forschungsgemeinschaft |
| | DFG |
| Identifier | G:(GEPRIS)141518795 |
⇧ TRR 60: Interaktion von Viren mit Zellen des Immunsystems bei persistierenden Virusinfektionen: Grundlagen für Immuntherapie und Impfungen ⇧
Note: We dealt with the molecular mechanisms how HBV manipulate innate immune responses by interfering TLR signaling, IFN-α production and signaling by modification of key molecules in the corresponding pathways. We will continue the analysis to identify the specific strategies targeting innate immune responses by HBV and explore these processes of restoring the effective antiviral mechanism, thus regaining control of HBV replication and finally curing HBV infection.
Recent Publications
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