CFEL-XOM

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2019-02-25
10:28
OpenAccess [PUBDB-2019-01243] Journal Article
et al
Multilayer Laue lenses at high x-ray energies: Performance and applications
Optics express 27(5), 7120 - 7138 () [10.1364/OE.27.007120]  GO
X-ray microscopy at photon energies above 15 keV is very attractive for the investigation of atomic and nanoscale properties of technologically relevant structural and bio materials. This method is limited by the quality of X-ray optics [...]
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2019-02-24
10:10
[PUBDB-2019-01225] Contribution to a book

Sub-micrometer Focusing and High-Resolution Imaging with Refractive Lenses and Multilayer Laue Optics
Synchrotron Light Sources and Free-Electron Lasers / Jaeschke, Eberhard (Editor) ; Cham : Springer International Publishing, 2019, Chapter 62-1 ; ISBN: 978-3-319-04507-8 ; doi:10.1007/978-3-319-04507-8 Cham : Springer International Publishing 1-28 () [10.1007/978-3-319-04507-8_62-1]  GO
In this chapter we describe the fundamentals of X-ray optics with a particular emphasis on refractive and diffractive optics for high-resolution X-ray microscopy. To understand the physical limitations of X-ray microscopy and X-ray optics, a wave-optical treatment of the interaction of X-rays with the optical elements is needed [...]

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2018-08-22
14:26
OpenAccess [PUBDB-2018-03102] Journal Article
et al
Megahertz serial crystallography
The new European X-ray Free-Electron Laser is the first X-ray free-electron laser capable of delivering X-ray pulses with a megahertz inter-pulse spacing, more than four orders of magnitude higher than previously possible. However, to date, it has been unclear whether it would indeed be possible to measure high-quality diffraction data at megahertz pulse repetition rates. [...]
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2018-05-31
16:00
OpenAccess [PUBDB-2018-02164] Journal Article
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Enzyme intermediates captured “on the fly” by mix-and-inject serial crystallography
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ddc:570
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2018-02-02
16:01
OpenAccess [PUBDB-2018-01024] Journal Article
et al
Femtosecond X-ray diffraction from an aerosolized beam of protein nanocrystals
High-resolution Bragg diffraction from aerosolized single granulovirus nano-crystals using an X-ray free-electron laser is demonstrated. The outerdimensions of the in-vacuum aerosol injector components are identical toconventional liquid-microjet nozzles used in serial diffraction experiments,which allows the injector to be utilized with standard mountings. [...]
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2017-10-24
11:53
OpenAccess [PUBDB-2017-11523] Journal Article
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Analysis of XFEL serial diffraction data from individual crystalline fibrils
IUCrJ 4(6), 795 - 811 () [10.1107/S2052252517014324]  GO
Serial diffraction data collected at the Linac Coherent Light Source from crystalline amyloid fibrils delivered in a liquid jet show that the fibrils are well oriented in the jet. At low fibril concentrations, diffraction patterns are recorded from single fibrils; these patterns are weak and contain only a few reflections [...]
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2017-10-05
15:34
[PUBDB-2017-11182] Journal Article
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Post-sample aperture for low background diffraction experiments at X-ray free-electron lasers
The success of diffraction experiments from weakly scattering samples strongly depends on achieving an optimal signal-to-noise ratio. This is particularly important in single-particle imaging experiments where diffraction signals are typically very weak and the experiments are often accompanied by significant background scattering. [...]
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2017-03-16
15:22
OpenAccess [PUBDB-2017-01394] Journal Article
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Double-flow focused liquid injector for efficient serial femtosecond crystallography
Serial femtosecond crystallography requires reliable and efficient delivery of fresh crystals across the beam of an X-ray free-electron laser over the course of an experiment. We introduce a double-flow focusing nozzle to meet this challenge, with significantly reduced sample consumption, while improving jet stability over previous generations of nozzles. [...]
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2016-12-19
13:19
OpenAccess [PUBDB-2016-06339] Journal Article
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Extreme ultraviolet resonant inelastic X-ray scattering (RIXS) at a seeded free-electron laser
In the past few years, we have been witnessing an increased interest for studying materials properties under non-equilibrium conditions. Several well established spectroscopies for experiments in the energy domain have been successfully adapted to the time domain with sub-picosecond time resolution. [...]
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2016-12-16
10:33
OpenAccess [PUBDB-2016-06266] Journal Article
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Structural enzymology using X-ray free electron lasers
Structural dynamics 4(4), 044003 () [10.1063/1.4972069]  GO
Mix-and-inject serial crystallography (MISC) is a technique designed to image enzyme catalyzed reactions in which small protein crystals are mixed with a substrate just prior to being probed by an X-ray pulse. This approach offers several advantages over flow cell studies. [...]
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