CFEL-I

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2017-11-21
18:55
[PUBDB-2017-12204] Dissertation / PhD Thesis
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Structural modification of solids by ultra-short X-ray laser pulses
1-252 (2017) = Dissertation, University of Hamburg, 2017
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2017-11-03
11:34
OpenAccess [PUBDB-2017-11676] Journal Article
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Pink-beam serial crystallography
ddc:500
Serial X-ray crystallography allows macromolecular structure determination at both X-ray free electron lasers (XFELs) and, more recently, synchrotron sources. The time resolution for serial synchrotron crystallography experiments has been limited to millisecond timescales with monochromatic beams. [...]
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2017-10-26
09:09
DBCoverage [PUBDB-2017-11560] Journal Article
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Hit detection in serial femtosecond crystallography using X-ray spectroscopy of plasma emission
ddc:530
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2017-10-24
11:53
OpenAccess [PUBDB-2017-11523] Journal Article
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Analysis of XFEL serial diffraction data from individual crystalline fibrils
IUCrJ 4(6), 795 - 811 (2017) [10.1107/S2052252517014324]  GO
ddc:530
Serial diffraction data collected at the Linac Coherent Light Source from crystalline amyloid fibrils delivered in a liquid jet show that the fibrils are well oriented in the jet. At low fibril concentrations, diffraction patterns are recorded from single fibrils; these patterns are weak and contain only a few reflections [...]
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2017-10-24
11:41
[PUBDB-2017-11522] Journal Article
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Identification of Phosphorylation Codes for Arrestin Recruitment by G Protein-Coupled Receptors
Cell 170(3), 457 - 469.e13 (2017) [10.1016/j.cell.2017.07.002]  GO
ddc:570
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2017-10-20
12:14
OpenAccess [PUBDB-2017-11466] Preprint/Report
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Femtosecond x-ray diffraction from an aerosolized beam of protein nanocrystals
[arXiv:1702.04014] ddc:530
We demonstrate near-atomic-resolution Bragg diffraction from aerosolized single granulovirus crystals using an x-ray free-electron laser. The form of the aerosol injector is nearly identical to conventional liquid-microjet nozzles, but the x-ray-scattering background is reduced by several orders of magnitude by the use of helium carrier gas rather than liquid. [...]
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2017-10-10
16:07
[PUBDB-2017-11258] Conference Presentation
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Laser-induced acoustic desorption of large molecules via tape-drive method
DPG-Frühjahrstagung SAMOP, Meeting locationHannover, Germany, 29 Feb 2016 - 4 Mar 20162016-02-292016-03-04
By dispersing molecular beams with strong electric fields, we can routinely produce pure samples of individual conformers or clusters according to their quantum state. Selected molecules can be further controlled using alignment and orientation by laser and static electric fields [1]. [...]
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2017-09-14
21:02
[PUBDB-2017-10788] Journal Article
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Structure determination based on continuous diffraction from macromolecular crystals
ddc:570
Bright and coherent X-ray sources, such free-electron lasers, have spurred large activities in developing new methods to obtain the structures of biological macromolecules. In particular, single-molecule diffraction is highly desired, as it would abolish the need for crystallization. [...]
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2017-09-14
10:07
DBCoverage [PUBDB-2017-10745] Journal Article
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Mix-and-diffuse serial synchrotron crystallography
IUCrJ 4(6), 769 - 777 (2017) [10.1107/S2052252517013124]  GO
ddc:530
Unravelling the interaction of biological macromolecules with ligands and substrates at high spatial and temporal resolution remains a major challenge in structural biology. The development of serial crystallography methods at X-ray free-electron lasers and subsequently at synchrotron light sources allows new approaches to tackle this challenge. [...]
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2017-09-08
07:44
[PUBDB-2017-10518] Journal Article
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Characterization of Protein Nanocrystals Based on the Reversibility of Crystallization
ddc:540
A new approach is described to screen for protein nanocrystals based on the reversibility of crystallization. Methods to characterize nanocrystals are in strong need to facilitate sample preparation for serial femtosecond X-ray nanocrystallography (SFX). [...]
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