CFEL-I

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2018-05-11
10:20
OpenAccess [PUBDB-2018-01940] Journal Article
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X-ray and UV radiation-damage-induced phasing using synchrotron serial crystallography
Specific radiation damage can be used to determine phases de novo from macromolecular crystals. This method is known as radiation-damage-induced phasing (RIP). [...]
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2018-03-03
03:58
[PUBDB-2018-01363] Journal Article
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Femtosecond X-ray Fourier holography imaging of free-flying nanoparticles
Nature photonics 12(3), 150 - 153 () [10.1038/s41566-018-0110-y]  GO
Ultrafast X-ray imaging on individual fragile specimens such as aerosols1, metastable particles2, superfluid quantum systems3 and live biospecimens4 provides high-resolution information that is inaccessible with conventional imaging techniques. Coherent X-ray diffractive imaging, however, suffers from intrinsic loss of phase, and therefore structure recovery is often complicated and not always uniquely defined4,5. [...]
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2018-02-09
08:45
OpenAccess [PUBDB-2018-01143] Journal Article
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Supersaturation-controlled microcrystallization and visualization analysis for serial femtosecond crystallography
Time-resolved serial femtosecond crystallography with X-ray free electron laser (XFEL) holds the potential to view fast reactions occurring at near-physiological temperature. However, production and characterization of homogeneous micron-sized protein crystals at high density remain a bottleneck, due to the lack of the necessary equipments in ordinary laboratories [...]
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2018-02-02
16:01
OpenAccess [PUBDB-2018-01024] Journal Article
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Femtosecond X-ray diffraction from an aerosolized beam of protein nanocrystals
High-resolution Bragg diffraction from aerosolized single granulovirus nano-crystals using an X-ray free-electron laser is demonstrated. The outerdimensions of the in-vacuum aerosol injector components are identical toconventional liquid-microjet nozzles used in serial diffraction experiments,which allows the injector to be utilized with standard mountings. [...]
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2018-01-11
14:38
OpenAccess [PUBDB-2018-00518] Journal Article
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Corrigendum: Double-flow focused liquid injector for efficient serial femtosecond crystallography
Serial femtosecond crystallography requires reliable and efficient delivery of fresh crystals across the beam of an X-ray free-electron laser over the course of an experiment. We introduce a double-flow focusing nozzle to meet this challenge, with significantly reduced sample consumption, while improving jet stability over previous generations of nozzles. [...]
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2018-01-11
10:51
OpenAccess [PUBDB-2018-00440] Journal Article
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MHz frame rate hard X-ray phase-contrast imaging using synchrotron radiation
Optics express 25(12), 13857 () [10.1364/OE.25.013857]  GO
Third generation synchrotron light sources offer high photon flux, partial spatial coherence, and ~10$^{−10}$ s pulse widths. These enable hard X-ray phase-contrast imaging (XPCI) with single-bunch temporal resolutions [...]
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2018-01-11
10:49
Embargoed OpenAccess [PUBDB-2018-00439] Journal Article
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Controlling Protein Orientation in Vacuum Using Electric Fields
Single-particle imaging using X-ray free-electron lasers is an emerging technique that could provide high-resolution structures of macromolecules in the gas phase. One of the largest difficulties in realizing this goal is the unknown orientation of the individual sample molecules at the time of exposure. [...]
Published on 2017-09-01. Available in OpenAccess from 2018-09-01.: Download fulltextPDF Download fulltextPDF (PDFA); Restricted: Download fulltextPDF Download fulltextPDF (PDFA);
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2018-01-10
17:50
Embargoed OpenAccess [PUBDB-2018-00385] Journal Article
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DNA-based construction at the nanoscale: emerging trends and applications
Nanotechnology 29(6), 062001 () [10.1088/1361-6528/aaa120]  GO
The field of structural DNA nanotechnology has evolved remarkably—from the creation of artificial immobile junctions to the recent DNA–protein hybrid nanoscale shapes—in a span of about 35 years. It is now possible to create complex DNA-based nanoscale shapes and large hierarchical assemblies with greater stability and predictability, thanks to the development of computational tools and advances in experimental techniques. [...]
Published on 2018-01-10. Available in OpenAccess from 2019-01-10.: Download fulltextPDF Download fulltextPDF (PDFA); Restricted: Download fulltextPDF;
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2018-01-10
14:41
[PUBDB-2018-00376] Journal Article
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Fabrication of diamond diffraction gratings for experiments with intense hard x-rays
The demands on optical components to tolerate high radiation dose and manipulate hard x-ray beams that can fit the experiment requirements, are constantly increasing due to the advancements in the available x-ray sources. Here we have successfully fabricated the transmission type gratings using diamond, with structure sizes ranging from few tens of nanometres up to micrometres, and aspect ratio of up to 20. [...]
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2018-01-02
08:52
Embargoed OpenAccess [PUBDB-2018-00001] Journal Article
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Thermal x-ray diffraction and near-field phase contrast imaging
epl 120(1), 16003 () [10.1209/0295-5075/120/16003]  GO
Using higher-order coherence of thermal light sources, the resolution power of standard x-ray imaging techniques can be enhanced. In this work, we applied the higher-order measurement to far-field x-ray diffraction and near-field phase contrast imaging (PCI), in order to achieve superresolution in x-ray diffraction and obtain enhanced intensity contrast in PCI. [...]
Published on 2017-12-27. Available in OpenAccess from 2018-12-27.: Download fulltextPDF Download fulltextPDF (PDFA); Restricted: Download fulltextPDF Download fulltextPDF (PDFA);
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