ASU

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2017-02-13
10:11
Embargoed OpenAccess [PUBDB-2017-00953] Journal Article
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Atomic Structure of Granulin Determined from Native Nanocrystalline Granulovirus Using an X-ray Free-Electron Laser
ddc:000
To understand how molecules function in biological systems, new methods are required to obtain atomic resolution structures from biological material under physiological conditions. Intense femtosecond-duration pulses from X-ray free-electron lasers (XFELs) can outrun most damage processes, vastly increasing the tolerable dose before the specimen is destroyed. [...]
Fulltext: Manuscript-6sept-figs - Download fulltextPDF Download fulltextPDF (PDFA); Table1 - Download fulltextPDF Download fulltextPDF (PDFA); Published on 2017-02-15. Available in OpenAccess from 2018-02-15.: Supplementary - Download fulltextPDF Download fulltextPDF (PDFA); Manuscript6_final - Download fulltextPDF Download fulltextPDF (PDFA); Restricted: Download fulltextPDF Download fulltextPDF (PDFA);

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2016-12-16
10:33
OpenAccess [PUBDB-2016-06266] Journal Article
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Structural enzymology using X-ray free electron lasers
ddc:530
Mix-and-inject serial crystallography (MISC) is a technique designed to image enzyme catalyzed reactions in which small protein crystals are mixed with a substrate just prior to being probed by an X-ray pulse. This approach offers several advantages over flow cell studies. [...]
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2016-11-10
11:16
OpenAccess [PUBDB-2016-04849] Journal Article
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A data set from flash X-ray imaging of carboxysomes
ddc:610
Ultra-intense femtosecond X-ray pulses from X-ray lasers permit structural studies on single particles and biomolecules without crystals. We present a large data set on inherently heterogeneous, polyhedral carboxysome particles. [...]
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