Journal Article

Antibodies that bind in a pH-dependent manner to their antigens show promise for enhanced neutralization potency and blocking capacity against extracellular targets. However, because the mechanisms governing pH-dependent antigen binding remain poorly understood, engineering approaches are often limited to incorporating histidine residues in the antibody complementarity-determining regions. [...]

Inclusive and differential cross sections for Higgs boson production in proton-proton collisions at a centre-of-mass energy of 13.6 TeV are measured using data collected with the CMS detector at the LHC in 2022, corresponding to an integrated luminosity of 34.7 fb$^{−1}$. Events with the diphoton final state are selected, and the measured inclusive fiducial cross section is ${\sigma }_{\text{fid}}={74}\pm {11}{\left({\text{stat}}\right)}_{-4}^{+5}\left({\text{syst}}\right)$ fb, in agreement with the standard model prediction of 67.8 ± 3.8 fb [...]

A search for resonances in top quark pair ($\mathrm{t}\overline{\mathrm{t}}$) production in final states with two charged leptons and multiple jets is presented, based on proton–proton collision data collected by the CMS experiment at the CERN LHC at $\sqrt{s} = 13\,\textrm{TeV}$, corresponding to 138 fb$^{−1}$. The analysis explores the invariant mass of the $\mathrm{t}\overline{\mathrm{t}}$ system and two angular observables that provide direct access to the correlation of top quark and antiquark spins. [...]

A first search is presented for vector-like leptons (VLLs) exclusively decaying into a light long-lived pseudoscalar boson and a standard model τ lepton. The pseudoscalar boson is assumed to have a mass below the τ$^{+}$τ$^{−}$ threshold, so that it decays exclusively into two photons [...]

Incoherent J/ψ photoproduction in heavy ion ultraperipheral collisions (UPCs) provides a sensitive probe of localized, fluctuating gluonic structures within heavy nuclei. This Letter reports the first measurement of the photon-nucleon center-of-mass energy (WγN) dependence of this process in PbPb UPCs at a nucleon-nucleon center-of-mass energy of 5.02 TeV, using 1.52 nb-1 of data recorded by the CMS experiment. [...]

Bound states of charm and anticharm quarks, known as charmonia, have a rich spectroscopic structure that can be used to probe the dynamics of hadron production in high-energy hadron collisions. Here, the cross section ratio of excited (ψ(2S)) and ground state (J/ψ) vector mesons is measured as a function of the charged-particle multiplicity in proton-lead (pPb) collisions at a center-of-mass (CM) energy per nucleon pair of 8.16 TeV. [...]

A search is performed for dark matter (DM) produced in association with a single top quark or a pair of top quarks using the data collected with the CMS detector at the LHC from proton-proton collisions at a center-of-mass energy of 13 TeV, corresponding to 138 fb$^{−1}$ of integrated luminosity. An excess of events with a large imbalance of transverse momentum is searched for across 0, 1 and 2 lepton final states [...]

A search for heavy neutral gauge bosons (Z′) decaying into a pair of tau leptons is performed in proton-proton collisions at s=13 TeV at the CERN LHC. The data were collected with the CMS detector and correspond to an integrated luminosity of 138 fb-1. [...]

Despite the f$_{0}$(980) hadron having been discovered half a century ago, the question about its quark content has not been settled: it might be an ordinary quark-antiquark (${{\rm{q}}}\overline{{{\rm{q}}}}$) meson, a tetraquark (${{\rm{q}}}\overline{{{\rm{q}}}}{{\rm{q}}}\overline{{{\rm{q}}}}$) exotic state, a kaon-antikaon (${{\rm{K}}}\overline{{{\rm{K}}}}$) molecule, or a quark-antiquark-gluon (${{\rm{q}}}\overline{{{\rm{q}}}}{{\rm{g}}}$) hybrid. This paper reports strong evidence that the f$_{0}$(980) state is an ordinary ${{\rm{q}}}\overline{{{\rm{q}}}}$ meson, inferred from the scaling of elliptic anisotropies (v$_{2}$) with the number of constituent quarks (n$_{q}$), as empirically established using conventional hadrons in relativistic heavy ion collisions. [...]

In a previous study, IOR-160 was identified as a potent dual inhibitor of CK2 and HDAC enzymes. In this study, we evaluated its selectivity and therapeutic potential. [...]